Thyroid nodules and cancer during pregnancy and the postpartum period
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Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer International Publishing
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Thyroid disorders occur in approximately 5% of pregnant women. Untreated thyroid disease in the mother makes an adverse outcome in pregnancy more likely to occur and may harm the newborn, but treatment can mitigate these consequences. Levothyroxine is frequently used as a treatment for hypothyroidism. In pregnant women, the treatment dose is generally higher than in nonpregnant patients. Hyperthyroid disease in pregnant women is typically treated by means of antithyroid agents, but caution is needed, since methimazole has an association with congenital defects and propylthiouracil raises the risk of toxicity to the liver in the mother. It is advised that pregnant women in the initial trimester be administered propylthiouracil, which can later be converted to methimazole treatment to decrease the likelihood of liver damage. The aim of treating under-or overactivity of the thyroid in pregnant women is to reach a euthyroid state as rapidly as possible and ensure this remains so for the entire pregnancy. Currently, intervention is not recommended in pregnant women suffering from autoimmune thyroiditis nor isolated hypothyroxinemia, provided there are no signs of hypothyroidism. It is usually safe practice to delay treating thyroid nodules or low-grade thyroid carcinoma until the end of pregnancy [1]. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.
Açıklama
Anahtar Kelimeler
Otolaryngology; Postpartum period; Pregnancy; Thyroid cancers; Thyroid nodules
Kaynak
ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation
WoS Q Değeri
Scopus Q Değeri
N/A