Thyroid nodules and cancer during pregnancy and the postpartum period

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Tarih

2022

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer International Publishing

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Thyroid disorders occur in approximately 5% of pregnant women. Untreated thyroid disease in the mother makes an adverse outcome in pregnancy more likely to occur and may harm the newborn, but treatment can mitigate these consequences. Levothyroxine is frequently used as a treatment for hypothyroidism. In pregnant women, the treatment dose is generally higher than in nonpregnant patients. Hyperthyroid disease in pregnant women is typically treated by means of antithyroid agents, but caution is needed, since methimazole has an association with congenital defects and propylthiouracil raises the risk of toxicity to the liver in the mother. It is advised that pregnant women in the initial trimester be administered propylthiouracil, which can later be converted to methimazole treatment to decrease the likelihood of liver damage. The aim of treating under-or overactivity of the thyroid in pregnant women is to reach a euthyroid state as rapidly as possible and ensure this remains so for the entire pregnancy. Currently, intervention is not recommended in pregnant women suffering from autoimmune thyroiditis nor isolated hypothyroxinemia, provided there are no signs of hypothyroidism. It is usually safe practice to delay treating thyroid nodules or low-grade thyroid carcinoma until the end of pregnancy [1]. © The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

Açıklama

Anahtar Kelimeler

Otolaryngology; Postpartum period; Pregnancy; Thyroid cancers; Thyroid nodules

Kaynak

ENT Diseases: Diagnosis and Treatment during Pregnancy and Lactation

WoS Q Değeri

Scopus Q Değeri

N/A

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