Polikistik over sendromunda gözyaşı testleri ve meybomiyan bez fonksiyonları
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Tarih
2012
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Polikistik over sendrom’lu (PKOS) hastalarda gözyaşı testleri ve meibomian bez fonksiyonlarını değerlendirmek. Gereç ve Yöntem: Kırıkkale Üniversitesi Tıp Fakültesi Hastanesi Kadın Hastalıkları ve Doğum Polikliniği’nde PKOS tanısı almış 53 hasta ve 25 sağlıklı birey sırasıyla PKOS ve kontrol gruplarını oluşturmak üzere çalışmaya alındı. İki grupta gözyaşı film stabilitesini değerlendirmek amacıyla gözyaşı kırılma zamanı (BUT) ölçümü ve lakrimal bez fonksiyonlarını değerlendirmek amacıyla Schirmer I testi kullanıldı. Ayrıca meibomianit bulguları not edilerek tüm veriler istatistiksel olarak karşılaştırıldı. Bulgular: İki grup arasında meibomianit görülme sıklığı, ortalama BUT skoru, düşük BUT (10 saniye) skorlu olgu oranı ve ortalama Schirmer test sonuçları açısından istatistiksel olarak anlamlı farklılıklar saptandı. Meibomianit görülme oranı PKOS grubunda %22,6, kontrol grubunda %10 oranında tespit edildi. BUT skoru ortalaması PKOS grubunda 12,123,47 saniye, kontrol grubunda 14,143,85 saniye idi (p0,002). Düşük BUT skoruna sahip olgu oranı PKOS grubunda %28,3 iken, kontrol grubunda %10 idi (p0,007). Schirmer I testinde filtre kağıdı ıslanma düzeyi PKOS grubunda ortalama 20,127,41 mm iken, kontrol grubunda ortalama 15,884,65 mm idi (p0,001). Polikistik over sendrom grubunda Schirmer sonuçları %3,8 olguda anormal, %3,8 olguda şüpheli, %92,5 olguda normal iken kontrol grubunda bu oranlar sırasıyla %2, %4, %94 idi (p0,05). Sonuç: Polikistik over sendromda hormonal dengesizliğin tetiklediği kuru göz bulgularına azımsanmayacak oranda rastlanılmaktadır. Bu nedenle PKOS tanısı alan hastaların göz polikliniğine yönlendirilip kuru göz açısından değerlendirilmesi önerilmelidir.
Aim: To evaluate tear function tests and meibomian gland functions in patients with Polycystic ovary syndrome (PCOS). Material and Method: Fifty-three patients diagnosed with PCOS by Obstetrics and Gynecology Department of Kırıkkale University Medical Faculty and 25 healthy individuals were included in the study, constituting PCOS and control groups, respectively. In both groups tear break-up time (BUT) measurements were done for evaluating the stability of tear film and Schirmer I test was used for lacrimal gland functions. Meibomianitis findings were also recorded and all data were compared statistically between the 2 groups. Result: There were statistically significant differences between the groups in terms of meibomianitis incidence, mean BUT score, the percentages of cases with low BUT score (<10 seconds) and mean Schirmer test results. Meibomianitis incidence was 22.6% in PCOS group and10% in the control group. Mean BUT score was 12.12±3.47 seconds in PCOS patients and 14.14±3.85 seconds in the control group (p0.002). The percentage of cases with low BUT score was 28,3% in PCOS group and 10% in the control group (p0.007). In Schirmer test mean filter paper moisturing level was 20.12±7.41 mm in PCOS group and 15.88±4.65 mm in the control group (p0.001). The Schirmer test scores in PCOS group were abnormal in 3.8%, suspicious in 3.8%, and normal in 92.5% of patients while those numbers were 2%, 4%, and 94% in the control group, respectively (p>0.05). Conclusion: In PCOS patients, dry eye findings triggered by hormonal instabilities are encountered at a rate that cannot be underestimated. Therefore patients with PCOS diagnosis should be referred to ophthalmology department for evaluation of dry eye.
Aim: To evaluate tear function tests and meibomian gland functions in patients with Polycystic ovary syndrome (PCOS). Material and Method: Fifty-three patients diagnosed with PCOS by Obstetrics and Gynecology Department of Kırıkkale University Medical Faculty and 25 healthy individuals were included in the study, constituting PCOS and control groups, respectively. In both groups tear break-up time (BUT) measurements were done for evaluating the stability of tear film and Schirmer I test was used for lacrimal gland functions. Meibomianitis findings were also recorded and all data were compared statistically between the 2 groups. Result: There were statistically significant differences between the groups in terms of meibomianitis incidence, mean BUT score, the percentages of cases with low BUT score (<10 seconds) and mean Schirmer test results. Meibomianitis incidence was 22.6% in PCOS group and10% in the control group. Mean BUT score was 12.12±3.47 seconds in PCOS patients and 14.14±3.85 seconds in the control group (p0.002). The percentage of cases with low BUT score was 28,3% in PCOS group and 10% in the control group (p0.007). In Schirmer test mean filter paper moisturing level was 20.12±7.41 mm in PCOS group and 15.88±4.65 mm in the control group (p0.001). The Schirmer test scores in PCOS group were abnormal in 3.8%, suspicious in 3.8%, and normal in 92.5% of patients while those numbers were 2%, 4%, and 94% in the control group, respectively (p>0.05). Conclusion: In PCOS patients, dry eye findings triggered by hormonal instabilities are encountered at a rate that cannot be underestimated. Therefore patients with PCOS diagnosis should be referred to ophthalmology department for evaluation of dry eye.
Açıklama
Anahtar Kelimeler
Göz Hastalıkları
Kaynak
MN Oftalmoloji
WoS Q Değeri
Scopus Q Değeri
Cilt
19
Sayı
1
Künye
Oğurel, R., Yıldız, G. S., Gökçınar, N. B., Örnek, K., Yücel, A., Noyan, V., Sağsöz, N. (2012). Polikistik over sendromunda gözyaşı testleri ve meybomiyan bez fonksiyonları. MN Oftalmoloji, 19(1), 36 - 40.
