The Impact of Various Types of Exercise on Lipid Metabolism in Patients with Type 2 Diabetes and Concurrent Overweight/Obesity: A Narrative Review

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dc.authoridDrenowatz, Clemens/0000-0002-3861-5364
dc.authoridAfolabi, Hafeez Abiola/0000-0002-1120-4100
dc.authoridBadicu, Georgian/0000-0003-4100-8765
dc.contributor.authorAl-mhanna, Sameer Badri
dc.contributor.authorGhazali, Wan Syaheedah Wan
dc.contributor.authorBatrakoulis, Alexios
dc.contributor.authorAlkhamees, Nouf H.
dc.contributor.authorDrenowatz, Clemens
dc.contributor.authorMohamed, Mahaneem
dc.contributor.authorGulu, Mehmet
dc.date.accessioned2025-01-21T16:45:35Z
dc.date.available2025-01-21T16:45:35Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground. Type 2 diabetes mellitus (T2DM) and obesity present substantial challenges to global public health, marked by their widespread prevalence and associated morbidities. The ensuing complications, including cardiovascular disease (CVD), metabolic syndrome, cancer, liver disease, and neurodegeneration, underscore the urgent need for effective preventive measures. Despite this, primary prevention of CVD in individuals with T2DM and obesity remains inadequate. Regular exercise emerges as a pivotal factor in ameliorating various cardiometabolic parameters, yet conflicting findings persist regarding the impact of exercise parameters (frequency, intensity, time, and type) on lipid homeostasis. Objectives. This review scrutinizes the effects of diverse exercise types and parameters on individuals with T2DM and concurrent obesity. A focus is placed on investigating the influence of exercise on conventional lipids, such as LDL-C, HDL-C, TG, total TC, and VLDL-C. The review briefly delves into the mechanisms underlying exercise-induced effects on lipids and lipoproteins. Methods. A literature search was conducted using the PubMed, Scopus, and Google Scholar databases. Results. Regular exercise is instrumental in elevating HDL-C levels while reducing TG, TC, VLDL, and LDL-C concurrently. Exercise mitigates CVD risk, lowers BMI, and enhances insulin resistance, depending on exercise types, volume, intensity, frequency, and duration. Conclusion. Future research must delve into the dose-response effects of real-world exercise programs to guide tailored interventions. This comprehensive understanding should inform clinicians and practitioners, empowering them to prescribe personalized exercise regimens for individuals grappling with compromised metabolic health.
dc.description.sponsorshipSchool of Medical Sciences of the Universiti Sains Malaysia
dc.description.sponsorshipThis research was supported by the School of Medical Sciences of the Universiti Sains Malaysia. The funding body had no involvement in the design, execution, interpretation, or publication of this research.
dc.identifier.doi10.61186/aassjournal.1324
dc.identifier.issn2322-4479
dc.identifier.urihttps://doi.org/10.61186/aassjournal.1324
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25679
dc.identifier.volume12
dc.identifier.wosWOS:001356734500011
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherAnnals Applied Sport Science
dc.relation.ispartofAnnals of Applied Sport Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectAerobic Exercise; Resistance Training; Physical Activity; Metabolic Syndrome
dc.titleThe Impact of Various Types of Exercise on Lipid Metabolism in Patients with Type 2 Diabetes and Concurrent Overweight/Obesity: A Narrative Review
dc.typeReview Article

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