The effects of statin therapy on pulse wave velocity measurements

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dc.contributor.authorSimsek V.
dc.contributor.authorDogru T.
dc.contributor.authorDemir V.
dc.contributor.authorSahin Ö.
dc.contributor.authorTulmaç M.
dc.contributor.authorEbinc H.
dc.contributor.authorYildirim N.
dc.date.accessioned2020-06-25T15:17:27Z
dc.date.available2020-06-25T15:17:27Z
dc.date.issued2014
dc.departmentKırıkkale Üniversitesi
dc.description.abstractSeveral studies have shown that positive effects of statins on pulse wave velocity parameters. However, there is few study about the comparison of the effectivity of statins on pulse wave velocity parameters. In the present study, we aimed to show the difference about the effects of long term atorvastatin and rosuvastatin therapy on aortic stiffness in patients with hyperlipidemia. A total of 104 hyperlipidemic patients were enrolled into the study. There were 50 patients in Group 1 (The patients treated with Atorvastatin 20 mg/day) (23 male and 27 female, mean age: 55.8 ± 10.3 years;, mean age: 52.7 ± 9.4 years) and 54 patients in Group 2 (The patients treated with Rosuvastatin 10 mg/day) (23 male and 31 female, mean age: 52.7 ± 9.4 years). All patients followed up to 12 months about their lipid profile and pulse wave analysis data. After 12 months, we found that rosuvastatin was of higher positive effects on arterial stiffness and reflection index parameters (Student T test, p=0.049 and =0.041, respectively ) We considered that, rosuvastatin was of greater ameliorative effect on vascular stiffness than that of atorvastatin in the patients with hyperlipidemia.en_US
dc.identifier.endpage2285en_US
dc.identifier.issn12056626
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-84905822142
dc.identifier.scopusqualityN/A
dc.identifier.startpage2271en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2374
dc.identifier.volume20en_US
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherCardiology Academic Pressen_US
dc.relation.ispartofExperimental and Clinical Cardiology
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEndothelial dysfunctionen_US
dc.subjectPulse wave analysisen_US
dc.subjectStatinsen_US
dc.titleThe effects of statin therapy on pulse wave velocity measurementsen_US
dc.typeArticle

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