The Effects of Platelet-Rich Plasma and Platelet-Rich Fibrin on Rabbit Auricular Cartilage Regeneration

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dc.contributor.authorKaraçayli, Ceren
dc.contributor.authorKarahan, Siyami
dc.contributor.authorKazkayasi, Mustafa
dc.contributor.authorKiliç, Rahmi
dc.date.accessioned2025-01-21T16:28:45Z
dc.date.available2025-01-21T16:28:45Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: This study aims to examine the impact of platelet-rich fibrin (PRF) and platelet-rich plasma (PRP) on the repair of cartilage tissue. The objective is to discover if these materials effectively boost the healing ability of cartilage tissue. Material and Methods: The study consisted of 18 male rabbits from New Zealand, all of whom were adults and white in color. The rabbits were partitioned into three study cohorts, each consisting of six rabbits. The study group was partitioned into subgroups A and B, each consisting of three rabbits. Cartilage of 10×10 mm2 was surgically removed from the ears of rabbits in all A subgroups. A 1 mm section of cartilage was removed from the outer edge of the excised cartilage to decrease its dimensions. The 8×8 mm cartilage acquired from the initial group was positioned in the exact location from whence it was extracted. Within all B subgroups, a section of cartilage measuring 10×10 mm2 was extracted from the ears of rabbits. In the initial cohort, a volume of 2 milliliters of PRP was administered onto the mucoperichondrium at the site where the cartilage was excised. In the second group, PRF was applied to the site where the cartilage was excised. No intervention was conducted on the area where cartilage was removed in the third group. A scoring system was used to evaluate degenerative changes in microscopic cartilage analysis. Results: There was no significant difference between the groups in terms of cartilage healing. Conclusion: PRP and PRF don’t improve healing of the cartilage tissue in ear. © 2024 Turkey Association of Society of Ear Nose Throat and Head Neck Surgery. Production and hosting by Türkiye Klinikleri.
dc.identifier.doi10.24179/kbbbbc.2024-104117
dc.identifier.endpage162
dc.identifier.issn1300-6525
dc.identifier.issue4
dc.identifier.scopus2-s2.0-85210821608
dc.identifier.scopusqualityQ4
dc.identifier.startpage154
dc.identifier.urihttps://doi.org/10.24179/kbbbbc.2024-104117
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23628
dc.identifier.volume32
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTurkiye Klinikleri
dc.relation.ispartofJournal of Ear Nose Throat and Head Neck Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectear cartilage; growth factors; platelet-rich fibrin; platelet-rich plasma; rabbits
dc.titleThe Effects of Platelet-Rich Plasma and Platelet-Rich Fibrin on Rabbit Auricular Cartilage Regeneration
dc.title.alternativeTrombositten Zengin Plazma ve Trombositten Zengin Fibrin Yapılarının Tavşan Kulak Kıkırdağı Rejenerasyonu Üzerindeki Etkilerinin Karşılaştırılması
dc.typeArticle

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