Discrimination of malignant and benign breast masses using computer-aided diagnosis from dynamic contrast-enhanced magnetic resonance imaging

dc.contributor.authorIkizceli, Turkan
dc.contributor.authorKaracavus, Seyhan
dc.contributor.authorErbay, Hasan
dc.contributor.authorYurttakal, Ahmet
dc.date.accessioned2025-01-21T16:27:18Z
dc.date.available2025-01-21T16:27:18Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: To reduce operator dependency and achieve greater accuracy, the computer-aided diagnosis (CAD) systems are becoming a useful tool for detecting noninvasively and determining tissue characterization in medical images. We aimed to suggest a CAD system in discriminating between benign and malignant breast masses. Methods: The dataset was composed of 105 randomly breast magnetic resonance imaging (MRI) including biopsy-proven breast lesions (53 malignant, 52 benign). The expectation-maximization (EM) algorithm was used for image segmentation. 2D-discrete wavelet transform was applied to each region of interests (ROIs). After that, intensity-based statistical and texture matrix-based features were extracted from each of the 105 ROIs. Random Forest algorithm was used for feature selection. The final set of features, by random selection base, splatted into two sets as 80% training set (84 MRI) and 20% test set (21 MRI). Three classification algorithms are such that decision tree (DT, C4.5), naive bayes (NB), and linear discriminant analysis (LDA) were used. The accuracy rates of algorithms were compared. Results: C4.5 algorithm classified 20 patients correctly with a success rate of 95.24%. Only one patient was misclassified. The NB classified 19 patients correctly with a success rate of 90.48%. The LDA Algorithm classified 18 patients correctly with a success rate of 85.71%. Conclusion: The CAD equipped with the EM segmentation and C4.5 DT classification was successfully distinguished benign and malignant breast tumor on MRI. © 2021 by The Medical Bulletin of İstanbul Haseki Training and Research Hospital The Medical Bulletin of Haseki published by Galenos Yayınevi.
dc.identifier.doi10.4274/haseki.galenos.2021.6819
dc.identifier.endpage195
dc.identifier.issn1302-0072
dc.identifier.issue3
dc.identifier.scopus2-s2.0-85106889161
dc.identifier.scopusqualityQ3
dc.identifier.startpage190
dc.identifier.urihttps://doi.org/10.4274/haseki.galenos.2021.6819
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23317
dc.identifier.volume59
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGalenos
dc.relation.ispartofHaseki Tip Bulteni
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectBreast cancer; Breast lesions; Computer-aided diagnosis; Magnetic resonance imaging; Segmentation
dc.titleDiscrimination of malignant and benign breast masses using computer-aided diagnosis from dynamic contrast-enhanced magnetic resonance imaging
dc.typeArticle

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