The relationship between body-mass index and Helicobacter pylori infection: a case-control study

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Tarih

2021

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objective: Helicobacter pylori infection is one of the most common infections worldwide. There are different opinions in the literature about\rthe relationship between H. pylori and obesity. In this study, we investigated the relationship between body-mass index (BMI) and H. pylori\rinfection.\rMaterial and Method: A cross-sectional study was conducted among patients who underwent endoscopic examinations at Tekirdağ Namık\rKemal University Faculty of Medicine Hospital in 2019. The prevalence of H. pylori infection was examined by biopsy. The relationship\rbetween BMI and H. pylori infection was analyzed.\rResults: 51.8% of the cases in our population were positive for H. pylori infection. On histopathological examination, acute and chronic\rinflammation findings were higher in H. pylori-positive cases compared to H. pylori-negative cases. The prevalence of H. pylori infection\rwas higher in patients with high BMI than those with low BMI. Statistical analysis showed a significant relationship between BMI and the\rprevalence of H. pylori infection (p<0.001), and there was a positive linear correlation between these two parameters (r=0.542). When the\rrisk factors were examined univariable, BMI was found to be a significant risk factor for H. pylori infection (p=0.008). Multivariable analysis\rresults revealed that BMI is an independent risk factor for H. pylori infection. (OR=1.32 (1.09-3.46), p=0.025).\rConclusion: Our results showed that there is a significant relationship between BMI and H. pylori infection, and high BMI is an independent\rrisk factor for H. pylori infection.

Açıklama

Anahtar Kelimeler

Biyoloji, Genel ve Dahili Tıp, Mikrobiyoloji

Kaynak

Journal of medicine and palliative care (Online)

WoS Q Değeri

Scopus Q Değeri

Cilt

2

Sayı

2

Künye