Coxiella burnetii seropositivity and coronary ectasia

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dc.contributor.authorDogru M.T.
dc.contributor.authorAlpay Y.
dc.contributor.authorSimsek V.
dc.contributor.authorUnal N.
dc.contributor.authorAskar S.
dc.contributor.authorEbinc H.
dc.contributor.authorYildirim N.
dc.date.accessioned2020-06-25T15:17:31Z
dc.date.available2020-06-25T15:17:31Z
dc.date.issued2014
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBacterial infections could contribute to atherosclerotic inflammation. We investigated the association of Coxiella Burnetii seropositivity with the atherosclerotic lesion types (obstructive and/or ectatic), serum lipid profile, nitric oxide (NO),total sulfhydryl (SH) groups and malonyldialdehyde (MDA) levels. A total of 150 participants (73 male, mean age: 56.6 ± 11.4 years; 77 female, mean age: 57.3 ± 13.0 years) were enrolled into the study. Coronary angiography was performed all the participants. We also performed serum lipid profile, NO, SH groups and MDA levels to determine the changes in chronic and acute Coxiella burnetii infections. The patients with obstructive and ectatic coronary artery lesions were of higher Coxiella phase I IgG titer (The marker of chronic Coxiella infection) than those of other coronary artery disease groups(One Way ANOVA, p=0.001). There were higher serum total cholesterol levels in the patients with chronic Coxiella infection than those of other patients. The chronic Coxiella Burnetii infection may be an important factor for the formation of coronary artery ectasia on basement of atherosclerotic coronary artery disease. Hyperlipidemia might also facilitate and augment this association.en_US
dc.identifier.endpage2302en_US
dc.identifier.issn12056626
dc.identifier.issue8en_US
dc.identifier.scopus2-s2.0-84905826482
dc.identifier.scopusqualityN/A
dc.identifier.startpage2286en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2402
dc.identifier.volume20en_US
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherCardiology Academic Pressen_US
dc.relation.ispartofExperimental and Clinical Cardiology
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAneurysmen_US
dc.subjectAtherosclerosisen_US
dc.subjectCoronary artery diseaseen_US
dc.subjectCoxiella burnetiien_US
dc.subjectHyperlipidemiaen_US
dc.titleCoxiella burnetii seropositivity and coronary ectasiaen_US
dc.typeArticle

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