Predictive value of c-reactive protein to albumin ratio and systemic immune-inflammation index for the long-term mortality in COVID-19

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dc.contributor.authorPolat, Esra
dc.contributor.authorŞabanoğlu, Cengiz
dc.contributor.authorCaner, Muhdedir
dc.contributor.authorUrkmez, Fatma Yekta
dc.contributor.authorİnanç, Fulden Akyüz
dc.contributor.authorÖztürk, Ünal
dc.contributor.authorKandemir, Hüseyin
dc.date.accessioned2025-01-21T16:11:43Z
dc.date.available2025-01-21T16:11:43Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: Several studies have investigated the association between biomarkers and short-term prognosis in the coronavirus infectious disease 2019 (COVID-19). However, data on the long-term prognosis are limited. To determine the predictive value of systemic immune-inflammation index (SII) and C-reactive protein (CRP) to albumin ratio (CAR) for in-hospital and 1-year outcomes during COVID-19. Material and Method: The primary outcomes were in-hospital and 1-year mortality. The secondary outcomes were the intensive care unit (ICU) need at admission and transfer to the ICU later on. Results: The study included 449 (53.6%) males and 389 (46.4%) females with a mean age of 53.8±18.5 years. Previously known heart failure (HF), COVID-19-related HF, acute renal failure (ARF), diabetes mellitus, hypertension, coronary artery disease (CAD), chronic obstructive pulmonary disease (COPD)/asthma, high CO-RADS scores (>4), low ejection fraction (EF), higher CAR and SII were associated with an increased in-hospital and 1-year mortality (p<0.05). After multivariate analysis; CAR, SII, ARF, and diabetes mellitus were independent predictors of in-hospital and 1-year mortality,whereas CAD was only an independent predictor of 1-year mortality. After ROC analysis, CAR cut-off levels of 2.54 and 2.23 predicted in-hospital and 1-year mortality, respectively (p<0.001). The SII cut-off levels of 1274 and 1191 predicted in-hospital and 1-year mortality, respectively (p<0.001). Conclusion: CAR and SII can be used as valuable prognostic indexes to predict both the short-term and long-term mortality in COVID-19.
dc.identifier.doi10.47582/jompac.1256098
dc.identifier.endpage132
dc.identifier.issn2717-7505
dc.identifier.issue2
dc.identifier.startpage126
dc.identifier.trdizinid1243184
dc.identifier.urihttps://doi.org/10.47582/jompac.1256098
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1243184
dc.identifier.urihttps://hdl.handle.net/20.500.12587/21545
dc.identifier.volume4
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofJournal of medicine and palliative care (Online)
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectTıbbi İnformatik
dc.subjectTıbbi Araştırmalar Deneysel
dc.subjectTıbbi Etik
dc.subjectMikrobiyoloji
dc.subjectSağlık Politikaları ve Hizmetleri
dc.subjectAcil Tıp
dc.titlePredictive value of c-reactive protein to albumin ratio and systemic immune-inflammation index for the long-term mortality in COVID-19
dc.typeArticle

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