Diffuse idiopathic skeletal hyperostosis (DISH): a clinical study

dc.contributor.authorÖğden, Mustafa
dc.contributor.authorYüksel, Ulaş
dc.contributor.authorAkkaya, Süleyman
dc.contributor.authorOppong, Jonathan
dc.contributor.authorKısa, Üçler
dc.contributor.authorBakar, Bülent
dc.contributor.authorÖzveren, Mehmet Faik
dc.date.accessioned2025-01-21T16:17:22Z
dc.date.available2025-01-21T16:17:22Z
dc.date.issued2019
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: Diffuse idiopathic skeletal hyperosteosis (DISH) characterized by formation of disseminated osteofites on vertebra in the absence of traumatic or post infectious changes is a chronic disease of unknown etiology. This study was aimed to investigate the biochemical relationship of DISH in patients with DISH.Material and Method: Eleven patients diagnosed with DISH (DIH group) and eleven patients with axial pain but without any vertebral disease (Control group) who applied to the neurosurgery clinic between the years 2016-2017 were enrolled in this retrospective study. HLA-B27 antigen positivity, erythrocyte sedimentation rate, leukocyte, basofil and eosinophil counts, C-reactive protein, phosphorus and calcium levels, and their results in individuals were investigated. Anteroposterior and lateral pelvis, knee, lateral foot radiograms showing extra-axial involvement were viewed.Results: Of the patients with DISH, one owing to difficulty in swallowing and another owing to quadriplegia as a result of cervical trauma underwent surgical therapy. Radiological investigations of this group revealed iliac involvement in four patients and patellar joint involvement in one patient. There was no difference between groups with respect to age, sex, leucocyte, basophil and eosinophil count, C-reactive protein, phosphorus and calcium levels. However there was a significant difference with respect to dysphagia and extra-axial involvement. No individual was positive for HLA-B27 antigen.Conclusion: Present study findings suggested that both acute and/ or chronic inflammatory processes have no place in the etiology of this disease.
dc.identifier.doi10.21601/ortadogutipdergisi.431357
dc.identifier.endpage113
dc.identifier.issn2548-0251
dc.identifier.issue2
dc.identifier.startpage107
dc.identifier.trdizinid401094
dc.identifier.urihttps://doi.org/10.21601/ortadogutipdergisi.431357
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/401094
dc.identifier.urihttps://hdl.handle.net/20.500.12587/22622
dc.identifier.volume11
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofORTADOĞU TIP DERGİSİ
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectGenel ve Dahili Tıp
dc.subjectSağlık Bilimleri ve Hizmetleri
dc.subjectRomatoloji
dc.titleDiffuse idiopathic skeletal hyperostosis (DISH): a clinical study
dc.typeArticle

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