Physiology of the Nose and Paranasal Sinuses

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dc.contributor.authorDinç, Mehmet Emre
dc.contributor.authorMuluk, Nuray Bayar
dc.contributor.authorVonakis, Becky M.
dc.date.accessioned2025-01-21T16:28:14Z
dc.date.available2025-01-21T16:28:14Z
dc.date.issued2019
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe nasal area filters out particles and humidifies the air that goes to the lungs. It also acts as first-line immunological protection enabling the exposure of the inspired air to the mucosal membranes that hold immunoglobulin A (IgA). Breathing in through the nose, the air travels cranially in the nasal area and interacts with the olfactory nerves, which produces the smell sensation that is very well related to the sense of taste. A problem in association with this system can result in nasal symptoms such as postnasal drainage, headaches, facial pressure, congestion, and sinus infections. The mucosa of the respiratory system consists of pseudostratified epithelium with hair cells, along with muciparous, strial, and basal cells. Hair cells are the most differentiated cells of the nasal mucosa. The ciliated columnar epithelial mucosa that lines the nasal area and paranasal sinuses continues with the squamous epithelium of the anterior nasal cavity and pharynx, respectively. Ciliated epithelium occupies a more significant portion of the anterior nasal area in the newborn and laryngectomized individuals compared to others indicating the squamous metaplasia of ciliated epithelium, which develops as a reaction to the trauma of environmental exposures. The respiratory epithelium, previously regarded as a physical barrier, is greatly engaged in the nasal-associated lymphoid tissue (NALT); actually, the epithelial cells express major histocompatibility complex class II antigens, and Langerhans-type dendritic cells in the submucosal layer can present antigens to and trigger T-lymphocytes by interleukin 1 (IL-1). In this chapter, physiology of the nose and paranasal sinuses is presented in detail. © Springer Nature Switzerland AG 2020.
dc.identifier.doi10.1007/978-3-030-21217-9_6
dc.identifier.endpage63
dc.identifier.isbn978-303021217-9
dc.identifier.isbn978-303021216-2
dc.identifier.scopus2-s2.0-85088293724
dc.identifier.scopusqualityN/A
dc.identifier.startpage57
dc.identifier.urihttps://doi.org/10.1007/978-3-030-21217-9_6
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23517
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherSpringer International Publishing
dc.relation.ispartofAll around the Nose: Basic Science, Diseases and Surgical Management
dc.relation.publicationcategoryKitap Bölümü - Uluslararası
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectEpithelium; Hair cells; Nasal-associated lymphoid tissue (NALT); Nose; Paranasal sinuses; Physiology
dc.titlePhysiology of the Nose and Paranasal Sinuses
dc.typeBook Chapter

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