Aripiprazol Tedavisine Yanıt Veren Obsesif Kompulsif Bozukluğu Olan Bir Tourette Sendromu Vakası
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Tarih
2015
Yazarlar
Dergi Başlığı
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Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Tourette bozukluğu (TB) çoğunlukla yineleyen motor ve vokal tiklerle karakterize bir hastalıktır. Uzun yıllar tedavisinde haloperidol, trifluoperazin ve pimozid gibi etki gücü yüksek olan klasik antipsikotik ilaçlar kullanılmış, şiddetli olgularda adrenerjik agonist olan klonidin ve guanfasin tercih edilmiştir. Son dönemde ise yan etki profilinin daha iyi olması, vaka sunumları ve kontrollü çalışmalarda etkinliğinin gösterilmesiyle risperidon, ziprasidon, olanzapin gibi atipik antipsikotikler yaygın olarak kullanılmaktadır. Biz direnç gösteren obsesif semptomları ve tikleri olan bir vakada mekanizması açısından hem tipiklerden hem de atipiklerden ayrılan aripiprazol kullanımına kısa sürede cevap veren bir Tourette bozukluğu olgusunu bildirmeyi amaçladık.
Tourettes disorder (TD) is a disease mostly characterized with repeated motor and vocal tics. While highly potent drugs such as trifluoperazin, pimozide, haloperidol etc. have been used for many years, adrenergic agonists such as clonidine and guanfacine have been preferred in the treatment of severe cases. Hence their high potency was proved in controlled trials and case reports and favourable side effect profiles of these agents, atypical antipsyh- chotics such as risperidon, ziprasidon and olanzapin are used commonly. We aimed to present a case of Tourette disorder with refractory obsessive symptoms and tics who was treated succesfully with aripiprazol which differs from other typical and atypical antipsychotics due to its action of mechanism.
Tourettes disorder (TD) is a disease mostly characterized with repeated motor and vocal tics. While highly potent drugs such as trifluoperazin, pimozide, haloperidol etc. have been used for many years, adrenergic agonists such as clonidine and guanfacine have been preferred in the treatment of severe cases. Hence their high potency was proved in controlled trials and case reports and favourable side effect profiles of these agents, atypical antipsyh- chotics such as risperidon, ziprasidon and olanzapin are used commonly. We aimed to present a case of Tourette disorder with refractory obsessive symptoms and tics who was treated succesfully with aripiprazol which differs from other typical and atypical antipsychotics due to its action of mechanism.
Açıklama
Anahtar Kelimeler
Psikiyatri
Kaynak
Journal of Mood Disorders
WoS Q Değeri
Scopus Q Değeri
Cilt
5
Sayı
2
