Effect of Gingko Biloba Extract (Egb761) Supplementation onHemato-Biochemical Parameters Following Acute TreadmillExercise in Rats

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dc.contributor.authorÇınar, Yasemin
dc.contributor.authorKabakçı, Ruhi
dc.contributor.authorŞenol, Ali
dc.date.accessioned2025-01-21T16:19:10Z
dc.date.available2025-01-21T16:19:10Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThis study was aimed to investigate the effect of Gingko biloba extract (EGb761) on hemato biochemical parameters following acute treadmill exercise in rats. Thirty-two male rats were dividedinto four groups with equal number of rats. The animals of control and exercise groups orallyreceived 2 cc/kg bw 0.9% saline while EGb761 and EGb761+exercise groups received 100 mg/kgbw EGb761 by oral gavage for 5 days/week for 4 weeks. On the last day of experiment, theanimals of the exercise groups were promoted to acute exhaustive exercise, and blood sampleswere collected by intracardiac puncture from all rats. Following the hematological analysis, plasmasamples were separated for biochemical analysis. The results showed that exercise, EGb761supplementation or both did not lead to alteration on red blood cells (RBC), packed cell volume(PCV), hemoglobin (HGB), mean corpuscular hemoglobin (MCH), and mean corpuscularhemoglobin concentration (MCHC) (P>0.05). However, acute exhaustive exercise reduced meancorpuscular cell volume (MCV) in rats while increased red cell distribution width (RDW) (P<0.05). Inaddition, plasma alanine aminotransferase (ALT) activity, total cholesterol, and total protein levelsdid not change in any group (P>0.05), and alkaline phosphatase (ALP) activity was significantlyincreased in exercise groups while glucose and triglyceride levels were decreased (P<0.05). Inconclusion, our results showed that acute exhaustive exercise affected MCV and RDW values,plasma ALP activity, glucose, and triglyceride levels. Gingko biloba extract supplementationameliorated only the exercise-induced changes in ALP activity and RDW value. Therefore, it issuggested that the effects of usage after exercise or different doses of EGb761 should beinvestigated in the future comprehensive studies.
dc.identifier.endpage102
dc.identifier.issn1308-9323
dc.identifier.issn2149-1712
dc.identifier.issue2
dc.identifier.startpage98
dc.identifier.trdizinid484766
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/484766
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23027
dc.identifier.volume35
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofFırat Üniversitesi Sağlık Bilimleri Veteriner Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectTamamlayıcı ve Entegre Tıp
dc.subjectBiyoloji
dc.subjectHematoloji
dc.subjectFizyoloji
dc.subjectSpor Bilimleri
dc.subjectVeterinerlik
dc.titleEffect of Gingko Biloba Extract (Egb761) Supplementation onHemato-Biochemical Parameters Following Acute TreadmillExercise in Rats
dc.typeArticle

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