The enzyme activity of alkaline phosphatase in gingival crevicular fluid of smokers and non-smokers with chronic periodontitis
Yükleniyor...
Tarih
2006
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmanın amacı sigara kullanımının kronik periodontitisli hastalarda klinik parametreler ile DOS ALP enzim aktivitesi üzerine etkisinin değerlendirilmesidir. Gereç ve Yöntem: Araştırma, sigara içen 22 hasta, hiç sigara içmemiş 19 hasta olmak üzere toplam 41 gönüllü hasta üzerinde yürütüldü. Bütün hastalardan gingival indeks (Gİ), plak indeksi (Pİ), sondalama cep derinliği (SCD), klinik ataşman kaybı (KAK) ve sondalamada kanama (SK) dahil klinik parametreler ve alkalen fosfataz (ALP) enzim aktivitesi değerlendirmeleri için dişeti oluğu sıvısı (DOS) örneklemeleri yapıldı. Bütün ölçümler 3. ve 6. aylarda tekrarlandı. Bulgular: 3. ve 6. aylardaki ölçümlerde sigara içmeyen grupta, Gİ ve SK ortalama değerleri istatistiksel olarak anlamlı bir şekilde daha yüksek bulunmuştur (P0.05). DOS ALP total aktivitesinin sigara içmeyenlerde 6. ayda istatistiksel olarak anlamlı bir şekilde daha yüksek olduğu ve sigara içen grupta ise DOS ALP total aktivitesinin 6. aya doğru azaldığı görülmüştür. Sonuç: Bu araştırmada sigara kullanımının DOS ALP total seviyesini azalttığı sonucuna varılmıştır.
Objective: The aim of this study was to evaluate the effects of smoking on clinical parameters and the gingival crevicular fluid (GCF) levels of alkaline phosphatase (ALP) in patients with chronic periodontitis after initial periodontal therapy. Material and Methods: The study base consisted of 41 volunteer patients including 22 current smokers and 19 non-smokers. The clinical parameters including plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL) were recorded and GCF samples were collected for analysis of ALP levels. At the 3rd and the 6th months all of these procedures were repeated. Results: In smokers, only CAL was significantly higher at the 3rd month compared to non-smokers (P<0.05). GI and BOP were higher in non-smokers than smokers in both periods (P<0.05). PI showed increases from initial to the 6th month in smokers (P<0.05). Total activity of ALP was significantly higher in non-smokers at the 6th month (P<0.05) and decreased from baseline to the 6th month in smokers (P<0.017). Conclusion: The present study demonstrated that cigarette smoking decreases ALP levels of GCF in smokers.
Objective: The aim of this study was to evaluate the effects of smoking on clinical parameters and the gingival crevicular fluid (GCF) levels of alkaline phosphatase (ALP) in patients with chronic periodontitis after initial periodontal therapy. Material and Methods: The study base consisted of 41 volunteer patients including 22 current smokers and 19 non-smokers. The clinical parameters including plaque index (PI), gingival index (GI), bleeding on probing (BOP), probing depth (PD), clinical attachment loss (CAL) were recorded and GCF samples were collected for analysis of ALP levels. At the 3rd and the 6th months all of these procedures were repeated. Results: In smokers, only CAL was significantly higher at the 3rd month compared to non-smokers (P<0.05). GI and BOP were higher in non-smokers than smokers in both periods (P<0.05). PI showed increases from initial to the 6th month in smokers (P<0.05). Total activity of ALP was significantly higher in non-smokers at the 6th month (P<0.05) and decreased from baseline to the 6th month in smokers (P<0.017). Conclusion: The present study demonstrated that cigarette smoking decreases ALP levels of GCF in smokers.
Açıklama
Anahtar Kelimeler
Diş Hekimliği
Kaynak
Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research)
WoS Q Değeri
Scopus Q Değeri
Cilt
30
Sayı
3
Künye
Erdemir, E., Duran, İ., Haliloğlu, S. (2006). The enzyme activity of alkaline phosphatase in gingival crevicular fluid of smokers and non-smokers with chronic periodontitis. Hacettepe Dişhekimliği Fakültesi Derg.(. Clinical Dentistry and Research), 30(3), 25 - 32.
