THE EFFECTS OF THE COMBINED ORAL CONTRACEPTIVES ON THE BONE MINERAL DENSITY OF REPRODUCTIVE AGE WOMEN

dc.contributor.authorYucer, Gokcen
dc.contributor.authorYucel, Aykan
dc.contributor.authorNoyan, Volkan
dc.contributor.authorBostanci, M. Suhha
dc.contributor.authorSagsoz, Nevin
dc.date.accessioned2025-01-21T16:45:26Z
dc.date.available2025-01-21T16:45:26Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: To determine the effects of combined oral contraceptives (COC's) on bone mineral density of women after 12 month treatment. Design: Comparison of the Bone Mineral Density (BMD) and serum Ca+2, osteocalcin, alkaline phosphatase, Vitamin D3 and urinary OH-proline levels. Setting: Kirikkale University Medical Faculty Hospital. Patients: Fifty patients of ages < 40 years who took combined oral contraceptive for 12 months. Intervention: Bone Mineral Density Measurements and comparison of these values at the beginning and after 12 month of COC treatment. Results: The serum level of Ca+2 significantly increased [p<0.05] at the time of observation in comparison to the basal level. The urinary excretion of OH-proline over 12 months significantly decreased [p<0.05] at the end of study. At 12th month, no significant difference was detected in lumbar, femur, and distal ulna-radius BMD values in comparison with basal values. The BMD of proximal ulna-radius significantly increased [p<0.05] at the end of twelve months in comparison to basal content. Conclusions: The contraceptive pill containing 20 mu g Ethinyl estradiol + 100 mu g Levonorgestrel has beneficial effects on the bone turnover and bone mineral density at proximal ulna-radius.
dc.identifier.endpage336
dc.identifier.issn2149-9322
dc.identifier.issn2149-9330
dc.identifier.issue4
dc.identifier.startpage332
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25648
dc.identifier.volume2
dc.identifier.wosWOS:000409139000013
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherGalenos Yayincilik
dc.relation.ispartofTurkish Journal of Obstetrics and Gynecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectcombined oral contraceptive; bone mineral density; OH-proline; proximal ulna-radius
dc.titleTHE EFFECTS OF THE COMBINED ORAL CONTRACEPTIVES ON THE BONE MINERAL DENSITY OF REPRODUCTIVE AGE WOMEN
dc.typeArticle

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