The relationship between serum homocysteine levels and development of coronary collateral circulation in patients with acute coronary syndrome

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dc.contributor.authorKaradeniz, Muhammed
dc.contributor.authorKaradeniz, Tuba Betül
dc.contributor.authorSarak, Taner
dc.contributor.authorAlp, Çağlar
dc.date.accessioned2025-01-21T16:17:10Z
dc.date.available2025-01-21T16:17:10Z
dc.date.issued2020
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: Homocysteine is an amino acid that plays a role in folate metabolism and inhibits endothelial cell proliferation which is important for angiogenesis. In this study, we aimed to investigate the relationship between serum homocysteine levels and coronary collateral development. Material and Method: Consecutive 176 patients, with acute coronary syndrome and chronic total occlusion, were divided into two groups according to coronary collateral development. Rentrop 0 and 1 were regarded as group I and Rentrop 2 and 3 as group II. Results: Plasma homocysteine levels were 18.2±7.0 ?mol/L in the group I and 15.7±5.1 ?mol/L in the group II. Univariate logistic regression analysis showed that mean platelet volume and homocysteine were associated with poor coronary collateral. Multivariate logistic regression analysis showed that homocysteine level was independently associated with poor coronary collateral circulation (OR 1.069 [95% CI 1.012-1.130]; p=0.018). Conclusion: In this study clearly demonstrates that high serum homocysteine level is associated with poor collateral development in patients with acute coronary syndrome.
dc.identifier.doi10.32322/jhsm.657326
dc.identifier.endpage99
dc.identifier.issn2636-8579
dc.identifier.issue2
dc.identifier.startpage92
dc.identifier.trdizinid485692
dc.identifier.urihttps://doi.org/10.32322/jhsm.657326
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/485692
dc.identifier.urihttps://hdl.handle.net/20.500.12587/22579
dc.identifier.volume3
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofJournal of health sciences and medicine (Online)
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectGenel ve Dahili Tıp
dc.subjectKimya
dc.subjectTıbbi
dc.subjectKalp ve Kalp Damar Sistemi
dc.titleThe relationship between serum homocysteine levels and development of coronary collateral circulation in patients with acute coronary syndrome
dc.typeArticle

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