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Öğe The analysis of anterior skull base from two different perspectives: coronal and reconstructed sagittal computed tomography(Int Rhinologic Soc, 2005) Arıkan, Osman Kürşat; Ünal, Birsen; Kazkayaşı, Mustafa; Koç, CanThe aim of the study was to determine the heights of the anterior skull base and the distances between the anterior nasal spine and the skull base at three levels by means of coronal and reformatted sagittal images of computed tomography. The present study was performed on coronal and reformatted sagittal CT scans of 30 patients with sinonasal complaints. On the coronal view, the heights of the cribriform plate, the roof of ethmoid, and lateral lamella and the medial take-off angle between the ethmoid roof and cribriform plate were measured at different levels. On the reformatted sagittal images the distances from the nasal spine to the anterior cranial base at three different levels were measured. Then, the side-to-side variability of these measurements was statistically compared. The variations with normal distribution and abnormal distribution were analysed by paired t test and Wilcoxon paired-signed rank test, respectively. A statistically significant difference was detected only between the right and left sides in the height of the lateral lamella at the crista galli level (p < 0.05). The lateral lamella at the crista galli level on the left side was higher than on the right side. No statistically significant differences between the left and the right sides were noted in the heights and the distances of other data (p > 0.05). The normal anatomy of the anterior skull base has been described in detail on coronal and reconstructed sagittal computed tomography. These measurements may be helpful in the presurgical evaluation of patients undergoing endoscopic sinus surgery to optimize surgical safety.Öğe Cerebral haemodynamics in patients with pseudoexfoliation glaucoma(Nature Publishing Group, 2005) Akarsu, Cengiz; Ünal, BirsenPurpose To evaluate the cerebral haemodynamics in patients with pseudoexfoliation glaucoma. Methods A total of 19 consecutive patients with pseudoexfoliation glaucoma and 19 age- and sex- matched healthy volunteers were recruited in a prospective comparative study. The affected eye in patients with unilateral glaucoma and the eye with more advanced lesions in patients with bilateral glaucoma were included in the study, and the ipsilateral middle cerebral arteries (MCA) were evaluated. While in the controls, the study eye and the ipsilateral MCA were chosen randomly. Measurements included systemic arterial pressure, heart rate, intraocular pressure (IOP), and transcranial colour Doppler parameters, including peak systolic velocity (PSV), end-diastolic velocity (EDV), time-averaged maximum velocity (TAMAX), resistivity index (RI), and pulsatility index (PI). Results The mean PSV, EDV, and TAMAX were significantly lower in the patients with pseudoexfoliation glaucoma than in healthy controls (P < 0.001, < 0.001 and < 0.001, respectively). Additionally, patients with pseudoexfoliation glaucoma had significantly higher PI and RI than healthy controls (P = 0.001 and 0.04, respectively). Systolic and iastolic blood pressures (P = 0.19 and 0.91, respectively) and heart rate (P = 0.06) were not different between the groups. The mean IOP were significantly higher in the glaucoma patients compared with the controls (P < 0.001). Conclusion This study suggests that pseudoexfoliation glaucoma is associated with a reduction in the blood flow velocity and elevation in the resistance of the MCA.Öğe Cerebral hemodynamics in ocular hypertension(Springer, 2005) Akarsu, Cengiz; Bilgili, Yasemin Karadeniz; Ünal, Birsen; Taner, Pelin; Ergin, Ahmet; Kara, Simay AltanPurpose: To evaluate the cerebral blood flow velocity in patients with ocular hypertension. Material and methods: Twenty-four ocular hypertensive patients and 24 age- and sex-matched healthy volunteers were recruited in a prospective comparative study. All subjects had normal findings on full-threshold visual field tests and clinically normal optic nerves. All patients with ocular hypertension had an intraocular pressure (IOP) of > 21 mmHg on three separate occasions without treatment. Systolic and diastolic blood pressure by cuff, heart rate by palpation, IOP by Goldmann applanation tonometry, central corneal thickness by ultrasound pachymetry, blood flow velocities, and pulsatility index of the ipsilateral middle cerebral artery by transcranial color Doppler were measured. Results: Systolic and diastolic blood pressures ( P= 0.40 and P= 0.45, respectively), heart rate ( P= 0.30), and central corneal thickness ( P= 0.23) were similar in each group. Peak and end-diastolic blood flow velocities in the middle cerebral artery did not differ between ocular hypertensives and controls ( P= 0.37 and P= 0.87, respectively). In addition, pulsatility index did not significantly differ between ocular hypertensives and controls ( P= 0.61). Conclusions: The results of this study suggest that ocular hypertension is not associated with reduction in blood flow velocity and elevation of resistance in the middle cerebral artery.Öğe Column of bertin: Normal sonographic findings(2005) Ünal, Birsen; Aktaş, Aykut; Bilgili, Yasemin; Yilmaz, ErdalIntroduction: We aimed to describe the normal and pathologic sonographic (US) findings of column of Bertin (CB). Materials and methods: The study was performed on sixty-six patients who had CB on CT. CB was found to be suspicious in 22 cases; with either hypoechoic, heterogeneous, bulging contour, increased vascularity or cystic areas on US. Patient underwent US and CT imaging following their initial CT and US examinations, respectively. On CT images, isodens and homogeneous texture, enhancement equal to renal cortex were accepted as normal findings. The thickness of CB on axial (AT) and longitudinal (LT) sonography images and the thickness of renal parenchyme (PT) on longitudinal images were measured. The ratio of AT to PT and LT to PT were calculated. Echogenity, vascularity, and contours of CB were evaluated on sonography. The data evaluated with Pearson and t tests. Results: CB was bilateral in 39, and double in 9 cases. Totally 136 CB were evaluated. In two sonographically suspicious CB, renal cell carcinoma (pathologically confirmed) and Bosniak type 2 cysts were detected. In LT, AT, LT/PT and AT/PT were 14.0+3.1 mm (maximum: 23.4mm), 13.2±2.9 mm (maximum: 21.8 mm), 1.1±0.19 (maximum: 1.56) and 1.0±0.17 (maximum: 1.67) in normal cases, 28 mm, 26 mm, 2.15 and 2 mm, in case with renal cell carcinoma. The correlation between thickness of CB and parenchyme was significant (AT-PT r=0.555, p<0.001, and LT-PT r=0.614, p<0.001). Peripheral vascularities were observed in all, central minute vascular focuses in 24 (18%), hypoechogenity in 12 (9.0%), bulging exterior contour in 9 (6%) CB. Conclusion: Increased vascularity, hypoechogenity, increased thickness of CB and thickness to parenchyme ratio are suspicious sonographic findings which may necessitate CT examination.Öğe Doppler sonography of the normal lacrimal gland(Wiley, 2005) Bilgili, Yasemin; Taner, Pelin; Ünal, Birsen; Simsir, İlknur; Kara, Simay Altan; Bayram, Merih; Alıcıoğlu, BanuPurpose. We used Doppler sonography to determine the resistance index (RI) and pulsatility index (PI) of the normal lacrimal artery (LA) in both females and males. We also compared the values obtained at various periods of reproductive life. Methods. The study was performed in 25 prepubertal girls, 28 females of reproductive age, and 27 postmenopausal women, 23 pregnant women, and 104 healthy males. Doppler sonography was used to determine the RI and PI of the LA. Results. The mean PI for the entire patient population was 1.48 +/- 0.60 and the RI was 0.72 +/- 0.09. The RI and PI values of the LA did not differ between males and females. Similarly, the mean RI and PI values of the LA did not change significantly between the various reproductive phases. Conclusion. The PI and Rl of the lacrimal gland are similar in both sexes. Moreover, they are not altered by changes in levels of sex steroids. (c) 2005 Wiley Periodicals, Inc. J Clin Ultrasound 33:123-126, 2005; Published online in Wiley InterScience (www.interscience.wiley.com).Öğe Effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics(B C Decker Inc, 2006) Arıkan, Osman Kürşat; Akarsu, Cengiz; Ünal, Birsen; Ergin, Ahmet; Koç, CanObjectives: To determine the effect of oxymetazoline nasal spray on intraocular pressure and retrobulbar hemodynamics in patients with open-angle glaucoma and to compare the results with those measured in healthy control participants. Study Design: Controlled, prospective clinical trial. Setting: University hospital. Methods: Thirty patients with open-angle glaucoma and 30 healthy volunteers as controls were topically self-administered oxymetazoline nasal spray three times a day (one spray in each nostril of 0.05% concentration) for 5 days continuously. Main Outcome Measures: Intraocular pressure and retrobulbar hemodynamics were measured in glaucomatous and normal eyes at baseline and at the end of oxymetazoline application. Results: Oxymetazoline nasal spray lowered intraocular pressure significantly in both the glaucoma group (p = .02) and the control group (p = .001) after 5 days of treatment. The systemic parameters in the glaucoma and control groups (systolic blood pressure, p = .14 and p = .17; diastolic blood pressure, p = .18 and p = .49; and pulse rate, p = .06 and p = .50, respectively) did not show statistically significant differences during the study period. Additionally, except with a significant decrease in the resistivity index of the central retinal artery in the glaucoma patients (p = .001), oxymetazoline nasal spray did not result in any significant changes in the retrobulbar hemodynamics in both the glaucoma and control groups. Conclusions: This study showed that a 5-day treatment with oxymetazoline nasal spray reduced intraocular pressure in both healthy controls and patients with glaucoma under treatment. In addition, it had no significant adverse effects on the retrobulbar hemodynamics.Öğe Effects of vardenafil on intraocular pressure and orbital hemodynamics(Mary Ann Liebert, Inc, 2007) Taner, Pelin; Başar, M. Murad; Ünal, Birsen; Batislam, Ertan\Purpose: The aim of this study was to investigate the effects of vardenafil on systemic blood pressure, intraocular pressure (IOP), and orbital hemodynamics. Methods: Twenty-one (21) volunteers suffering erectile dysfunction, with an average age of 51.5 +/- 6.2 years, were enrolled into the study. Brachial blood pressures and IOP were measured, the peak systolic velocity (PSV), end-diastolic velocity (EDV), and resistive index (RI) of the ophthalmic, central retinal, and posterior ciliary arteries were evaluated by color Doppler ultrasonography (CDU) before vardenafil intake. All measurements were repeated after 20 min of vardenafil intake. A paired Student t test was used to evaluate the changes. Results: Systolic blood pressure did not change significantly where diastolic blood pressure decreased significantly (P = 0.043) after drug ingestion. There was no significant change in IOP. Increase in EDV of CRA was significant (P = 0.04), but the increase of orbital blood flow velocities of OA and PCA were insignificant. Conclusions: The recommended dose of vardenafil has no negative effects on orbital hemodynamics and IOP in patients with erectile dysfunction.Öğe Focal liver lesions evaluated by MR imaging(2006) Bilgili, Yasemin; Firat, Zeynep; Pamuklar, Ertan; Ünal, Birsen; Hyslop, William; Rivero, Hedrick; Semelka, Richard C.Magnetic resonance signal intensity of focal liver lesions is the result of their histological and cytological features. Therefore, analysis of lesion signal intensity and enhancement patterns obtained with magnetic resonance imaging is essential for the differential diagnosis of focal liver lesions. In this article, we review the magnetic resonance imaging features of the most common focal liver lesions. © Turkish Society of Radiology 2005.Öğe Giant abdominal wall abscess dissecting into thorax as a complication of ESWL(Elsevier Science Inc, 2005) Ünal, Birsen; Kara, Simay; Bilgili, Yasemin; Basar, Halil; Yiılmaz, Erdal; Batislam, ErtanAbscess as a complication of extracorporeal shock wave lithotripsy is a rare condition, We present the computed tomography findings of an abdominal wall abscess that occurred after extracorporeal shock wave lithotripsy for which prophylactic antibiotics had not been given. The abscess destroyed the posterior abdominal wall muscles and dissected into the thorax. The muscles were thickened and showed enhancement. A parenchymal defect in the right kidney adjacent to a caliceal stone, with strands extending from this defective region to the abscess, was observed, and was thought to be the result of parenchymal destruction caused by the shock waves. Other parts of the kidney and psoas muscle were normal. Microbiologic examination revealed Escherichia coli. UROLOGY 65: 389.e16-389.e18, 2005. (C) 2005 Elsevier Inc.Öğe Kolonun BT'de saptanan anatomik varyasyonları(2004) Ünal, Birsen; Kara, Simay; Aktaş, Aykut; Bilgili, YaseminAMAÇ Abdomen BT incelemelerinde saptanan kolonun anatomik varyasyonlarının insidansını ve görünümlerini sunmak. GEREÇ VE YÖNTEM Bölümümüzde ardı ardına çekilen 296 abdomen BT incelemesinde retrorenal kolon, retrogastrik kolon (hepatopankreatik interpozisyon veya retrosplenik kolon), yüksek yerleşimli sağ kolon ve kolonun böbrek ile psoas kası arasına ve hepatodiyafragmatik (anterior veya posterior) interpozisyonu araştırıldı. BULGULAR Biri pankreatikogastrik (%0.3), diğeri retrosplenik (%0.3) 2 olguda retrogastrik kolon; 2 olguda (%0.7) böbrek ile psoas kası arasına interpozisyon; 2 olguda iki taraflı, 3 olguda tek taraflı retrorenal kolon (%1.2); 1 olguda posterior (%0.3), 6 olguda (%2.1) anterolateral hepatodiyafragmatik interposizyon; 4 olguda çekum tamamen subhepatik, 8 olguda sağ alt kadran ile karaciğer arasında ara bir bölgede olmak üzere 12 olguda (%4.2) yüksek yerleşimli sağ kolon saptandı. Subhepatik yerleşimli çekum olan olgulardan birinde terminal ileum Morrison boşluğunda, diğerinde renal hilus anteriorunda yerleşmekteydi. SONUÇ Kolonun yerleşim varyasyonlarının rotasyon ve fiksasyondaki hafif embriyolojik anormallikler, kısa transvers mezokolon, intraperitoneal asendan veya desendan kolon, abdomen içi basınç artışı ve retroperitoneal yağ dokusu miktarının azalması gibi nedenlere bağlı geliştiği düşünülmektedir. Kolonun pankreatikogastrik interpozisyonu %0.2, retrosplenik yerleşimi %0.03-0.3, kısmi retrorenal yerleşim %9-10, tam retrorenal yerleşim %1, böbrek ile psoas kası arasına interpozisyonu sağda %1.7 solda %0.7, anterolateral hepatodiyafragmatik interpozisyon %1.3-3 oranlarında gözlenebilmektedir. Atipik yerleşimli kolon, patolojik olduğunda tanı hatalarına yol açabilir. Küçük omentumda yerleştiğinde patolojik olmasa da, bu bölgenin birçok patolojisinin görünümünü taklit edebilir. İntravenöz ürografi tetkiklerinde kitle imajı yaratabilir. Karaciğer, böbrek, dalak veya safra kesesi perkütan girişimlerinde ve cerrahisinde kolon perforasyonu oluşabilir. Bu nedenlerle BT incelemelerinde kolonun atipik yerleşimleri araştırılmalıdır.Öğe MRG ile normal görünümlü beyaz ve gri cevherde yaşlanmanın etkilerinin ADC değerleri ile saptanabilirliği(2004) Bilgili, Karadeniz Yasemin M.; Ünal, Birsen; Kendi, Tuba; Şimşir, İlknur; Erdal, Haydar; Huvaj, Sinef; Kara, SimayAMAÇ Çalışmamızda, MRG ile normal görünümlü beyaz ve gri cevherde, yaşlanma ile beyin dokusunda izlenen mikroskopik değişikliklerin, su difüzyonu değerinin matematiksel ölçümü olan ADC değeri (apparent diffusion coefficient= görünürdeki difüzyon katsayısı) ile saptanabilirliği araştırılmıştır. GEREÇ VE YÖNTEM MRG ve difüzyon ağırlıklı tetkikleri doğal olan, dekadlara göre sekiz alt gruba ayrılan 45 hastanın, "trace" ağırlıklı ADC haritaları kullanılarak, frontal ve oksipital beyaz cevherden ve talamustan ADC değerleri elde olundu. Elde olunan ADC değerlerinin artan hasta yaşı ile istatistiksel fark gösterip göstermediği araştırıldı. ADC ortalama değeri frontal beyaz cevherde 0.753±0.054 x 10-3 mm2/sn, okspital beyaz cevherde 0.673±0.085 x 10-3 mm2/sn, talamusta 0.763±0.063 x 10-3 mm2/sn olarak saptanmıştır. Frontal ve oksipital beyaz cevherde yaşla birlikte ADC değerlerinde istatistiksel olarak anlamlı artış saptanmış olmakla birlikte, talamusta yaşla ADC değerlerinde saptanan artış istatistiksel olarak farklılık oluşturmamaktadır. SONUÇ İlerleyen yaşla birlikte, MRG ile normal olarak saptanan beyaz cevherde, difüzyon ağırlıklı seriler ile su difüzyonunda artış saptanmış olup, bu veri yaşlanmanın getirdiği yapısal değişikliğin yansıması olarak düşünülmüştür.Öğe Osteomeatal kompleks boşluklarının/mesafelerinin kemik ve mukozal genişliklerinin kronik sinüzit şiddeti ile ilişkisi - BT çalışması(2005) Ünal, Birsen; Arıkan, Osman Kürşat; Bilgili, Yasemin; Koç, CanAmaç: Etmoid infindibulum ve unsinat proses-orta konka boşluklarının kemik ve mukozal genişlikleri ve lamina paprisea-orta konka mesafesinin kemik genişliği ile maksiller, ön etmoid ve frontal sinüs patolojilerinin şiddeti arasındaki ilişki araştırıldı. Yöntem ve Gereçler: Kronik sinüziti olan 49 hastanın paranazal sinüs bilgisayarlı tomografilerinden etmoid infindibulum ve unsinat proses-orta konka boşluklarının kemik ve mukoza konturları arasındaki mesafe ile lamina paprisea-orta konka mesafesi toplam 98 nazal yarıda ölçüldü. İnflamatuar patolojiler sinüs hacmindeki azalmaya göre yok, hafif (sinüs hacminin 1/3’ünden azı kapalı), orta (sinüs hacminin 1/3’ü ile 2/3’ü kapalı) ve şiddetli (2/3’ünden fazlası kapalı) olarak gruplandı. Osteomeatal kompleks düzeyinde bulunan septum deviasyonu, etmoid bulla overpnömatizasyonu, Haller hücresi, unsinat proses deviasyonu ve pnömatizasyonu, bulbar konka bulloza varlığı gibi anatomik varyasyonlar kaydedildi. Bulgular: Şiddetli maksiller ve ön etmoid sinüs patolojisi olanlarda kemik infindibulum ve mukozal infindibulum genişlikleri, şiddetli-orta derecede frontal sinüs patolojisi saptanan olgularda ise mukozal infindibulum genişliği, patoloji saptanmayanlara oranla dardı (p0.05). Kemik infindibulum genişliği ile maksiller sinüzit şiddeti, mukozal infindibulum genişliği ile frontal, maksiller ve ön etmoid sinüzitlerin şiddeti ve mukozal unsinat proses-orta konka genişliği ile frontal sinüzit şiddeti arasında negatif ilişki saptandı. Otuzbeş (%71.4) olguda bir veya daha fazla anatomik varyasyon gözlendi. Lamina paprisea-orta konka ve mukozal infindibulum genişlikleri anatomik varyasyon olan yarı sinüslerde olmayan tarafa göre dardı. Sonuç: Osteomeatal kompleks mukozal patolojilerinin yanında kemik yapılar arası mesafelerdeki azalmalar da sinüs inflamatuar patolojilerinde rol oynamaktadır. Kemik infindibulum aralığının daralması maksiller sinüzit gelişimi ve ilerlemesi için önemli bir faktör olarak göze çarpmaktadır.Öğe Prevalence of primary tethered cord syndrome associated with occult spinal dysraphism in primary school children in Turkey(Karger, 2006) Bademci, Gülşah; Saygun, Meral; Batay, Funda; Çakmak, Aytul; Basar, Halil; Anbarci, Hüseyin; Ünal, BirsenThe prevalence and associated factors of primary tethered cord syndrome (PTCS) in primary school children were investigated. A cross-sectional study was performed in four demographically different primary schools in Turkey. Demographic, familial and physical data were collected from 5,499 children based on enuresis as a predominant symptom and dermatologic and orthopedic signs as clues of occult spinal dysraphism. Statistical analysis and input of the data were carried out with the SPSS package program 10.00, and logistic regression analysis was used to identify discriminating factors between enuretic children with or without neurologic signs. Of 5,499 analyzed children, 422 (7.7%) had enuresis nocturna, and 19.9% of 422 children had also daytime incontinence. Sixteen of these 422 enuretic children (3.8%) had several dermatologic signs. Five of them had spina bifida on plain radiographies, and 4 of them had cord tethering on lumbar MRI. Fifteen of 422 enuretic children (3.7%) had gait disturbances and orthopedic anomalies without cutaneous manifestations. Six of 15 children had spina bifida on plain graphies and 2 of them had tethered cord syndrome on MRI. The general prevalence of PTCS was found to be 0.1% of 5,499 analyzed children and 1.4% of enuretic children. A good outcome after untethering was found in 83.0% in this series. Practitioners should be aware of these clues of occult spinal dysraphism and resort to further radiologic and neurosurgical assessment. Early surgical intervention may halt the progression of the neurologic deficits and stabilize or reverse symptoms. Copyright (c) 2006 S. Karger AG, Basel.Öğe Risky anatomic variations of sphenoid sinus for surgery(Springer, 2006) Ünal, Birsen; Bademci, Gülşah; Bilgili, Yasemin K.; Batay, Funda; Avcı, EmelWe searched for the surgically risky anatomic variations of sphenoid sinus and aimed to compare axial and coronal tomography in detection of these variations. Fifty-six paranasal tomography images (112 sides) were evaluated for coronal, axial and both coronal and axial images. Tomographic findings including bony septum extending to optic canal or internal carotid artery; protrusions and dehiscences of the walls of internal carotid artery, optic nerve, maxillary nerve and vidian nerve; extreme medial course of internal carotid artery; patterns of aeration of the anterior clinoid process; and Onodi cells were evaluated. The results were classified as "present, absent, suspicious-thin (only for dehiscence) or no-consensus". The results of each plane were compared with that of the result of the both planes together. Kappa coefficient and Chi-square tests were used to compare both planes. Twelve cadaveric dissections were performed to reveal the proximity of sphenoid sinus to surgically risky anatomic structures. Endoscopy was applied to five cadavers. 18 evaluations were classified as 'no-consensus'. We detected 34, 35, 34 and 40 protrusions of internal carotid artery, optic nerve, maxillary nerve, vidian nerve, respectively. Dehiscences were present in 6, 9, 4 and 8, and suspicious-thin in 8, 10, 16 and 25 in canals of internal carotid artery, optic nerve, maxillary nerve and vidian nerve, respectively. Bony septum to internal carotid artery and optic nerve was observed in 30 and 22 cases. We observed 9 extreme medial courses of internal carotid artery, 27 aerated clinoid process and 9 Onodi cells. Axial images were superior in detection of bony septum to internal carotid artery and Onodi cells; while the coronal images were more successful in detection of protrusion of optic nerve and vidian nerve, and dehiscense of maxillary nerve and vidian nerve (P < 0.05). In cadaveric dissections, the septa were inserted into the bony covering of the carotid arteries in two sinuses (8.3%). Detailed preoperative analysis of the anatomy of the sphenoid sinus and its boundaries is crucial in facilitating entry to the pituitary fossa and reducing intraoperative complications. Coronal tomography more successfully detects the sphenoid sinus anatomic variations.Öğe Topikal fenilefrin ve siklopentolat'ın orbita kan akımı üzerine etkisi(2005) Ünal, Birsen; Akarsu, Cengiz; Bilgili, Yasemin; Kara, Simay; Taner, Pelin; Ergin, AhmetAmaç: Topikal uygulanan siklopentolat ve fenilefrin'in retrobulber kan akım hızlarına olan etkisini renkli Doppler ultrasonografi ile araştırmak. Gereç ve Yöntem: Göz polikliniğine başvuran hastalardan seçilen 22 gönüllü olgu siklopentolat grubunu, 40 olguda fenilefrin grubunu oluşturdu. Olguların rasgele seçilen bir gözlerine siklopentolat veya fenilefrin, diğer gözlerine ise serum fizyolojik damlatıldı. İlaç uygulanmadan önce renkli Doppler görüntüleme ile oftalmik arter, posterior silier arter ve santral retinal arterde maksimum sistolik kan akım hızı, diyastol sonu kan akım hızı, rezistivite ve pulsatilite indeksleri saptandı. İlaç uygulamasından önce elde edilen değerler, ilaç sonrası elde edilen değerler ile istatistiksel olarak karşılaştırıldı. Bulgular: İlaç uygulamaları sonrasında her iki grupta, sistemik parametreler ve göz içi basıncı açısından anlamlı bir fark saptanmadı (p0.05). Siklopentolat uygulanan grupta, ilaç öncesi ve sonrası retrobulber kan akım hızları anlamlı farklılık göstermedi (p0.05). Fenilefrin uygulanan grupta, ilaç uygulanan gözde diyastol sonu kan akım hızı kontrol göze göre posterior silier arterde anlamlı derecede düşük bulundu (p0.034). Bunun dışında her iki grupta yapılan kan akım hız ölçümlerinde anlamlı olmayan hafif düşme, rezistivite ve pulsatilite indekslerinde ise anlamlı olmayan hafif artış saptandı (p0.05). Sonuç: Her iki ilaç göz içi basınç, sistemik kan basıncı ve retrobulber kan akımında belirgin değişiklik yaratmamaktadır. Ancak, orbital hemodinamik bozukluk gösteren olgular üzerinde yapılacak yeni çalışmalar her iki ilacın bu olgulardaki etkileri konusuna açıklık getirecektir.Öğe Uterus didelfis ve renal agenezis(2003) Bilgili, Yasemin; Ünal, Birsen; Bayram, Merih; Şimşir, İlknur; Kara, Simay AltanAmaç: Alt kadran ağrısı ile başvuran 15 yaşındaki kadın hastanın US ve MRG ile değerlendirilmesi. Materyal ve Metod: Karın ağrısı etiyolojisinin saptanabilmesi için olguya US ve MRG tetkikleri yapıldı. Bulgular: US ve MRG yapılması ile olguda, uterus didelfis, unilateral vajinal subseptus ve ipsilateral renal agenezis saptandı. Sonuçlar:US ve MRG alt kadran ağrısının etiyolojisinin aydınlatılmasında, tedavinin planlanmasında ve fertilitenin korunarak gereksiz cerrahi işlemlerden hastanın korunmasında önem taşımaktadır.
