Cerebral hemodynamics in ocular hypertension

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Küçük Resim

Tarih

2005

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Purpose: To evaluate the cerebral blood flow velocity in patients with ocular hypertension. Material and methods: Twenty-four ocular hypertensive patients and 24 age- and sex-matched healthy volunteers were recruited in a prospective comparative study. All subjects had normal findings on full-threshold visual field tests and clinically normal optic nerves. All patients with ocular hypertension had an intraocular pressure (IOP) of > 21 mmHg on three separate occasions without treatment. Systolic and diastolic blood pressure by cuff, heart rate by palpation, IOP by Goldmann applanation tonometry, central corneal thickness by ultrasound pachymetry, blood flow velocities, and pulsatility index of the ipsilateral middle cerebral artery by transcranial color Doppler were measured. Results: Systolic and diastolic blood pressures ( P= 0.40 and P= 0.45, respectively), heart rate ( P= 0.30), and central corneal thickness ( P= 0.23) were similar in each group. Peak and end-diastolic blood flow velocities in the middle cerebral artery did not differ between ocular hypertensives and controls ( P= 0.37 and P= 0.87, respectively). In addition, pulsatility index did not significantly differ between ocular hypertensives and controls ( P= 0.61). Conclusions: The results of this study suggest that ocular hypertension is not associated with reduction in blood flow velocity and elevation of resistance in the middle cerebral artery.

Açıklama

Anahtar Kelimeler

Kaynak

Graefes Archive For Clinical And Experimental Ophthalmology

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

243

Sayı

4

Künye

closedAccess