The Frequency of Hepatitis B, Hepatitis C and Hepatitis G Virus in Patients with Beta-Thalassemia Major Who Receive Frequent Blood Transfusion

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dc.contributor.authorSanli, Cihat
dc.contributor.authorAlbayrak, Meryem
dc.contributor.authorNakipoglu, Fikret
dc.contributor.authorGumruk, Fatma
dc.date.accessioned2025-01-21T16:45:32Z
dc.date.available2025-01-21T16:45:32Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThe purpose of this study is to investigate the frequency of hepatitis B (HBV), hepatitis C (HCV) and hepatitis G (HGV) virus, the demographical characteristics and clinical information of patients with beta-thalassemia major who receive frequent blood transfusion. Seventy patients with beta-thalassemia major [36 (51.5%) male, 34 (48.5%) female] are included in our study. The age of the patients was between two and 24 years. Age, gender and clinical information (time of first transfusion, number of transfusions and hepatitis B vaccination) of the patients are recorded. HBsAg, anti-HBs, anti-HBc IgG, HBV-DNA, anti-HCV, HCV-RNA and HGV-RNA tested in all patients. Three (4.3%) patients tested HGV-RNA positive. HBsAg in 1 (1.4%) patient, anti-HBs in 66 (94.3%) patients, anti-HBc IgG in 23 (% 32.9) patients, anti-HCV in14 (20%) patients and in 5 (7.1%) HCV-RNA tested positive. There was no relationship between HGV-RNA positivity and factors such as age, gender, number of transfusion, time of first transfusion, serum ferritin or serum ALT levels. While average serum ALT levels of two patients with both HGV-RNA and HCV-RNA positive was higher than the other patients. In 4.3% of the patients who received frequent blood transfusion the HGV-RNA was detected. While HGV infection can co-exist with HBV and HCV infections, however, when it exists alone, pronounced increase in transaminase levels had not occured.
dc.identifier.endpage157
dc.identifier.issn1307-9441
dc.identifier.issn2147-2939
dc.identifier.issue3
dc.identifier.startpage150
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25671
dc.identifier.volume10
dc.identifier.wosWOS:000217138900005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotr
dc.publisherGalenos Yayincilik
dc.relation.ispartofViral Hepatit Dergisi-Viral Hepatitis Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectThalassemia; hepatitis B; hepatitis C; hepatitis G
dc.titleThe Frequency of Hepatitis B, Hepatitis C and Hepatitis G Virus in Patients with Beta-Thalassemia Major Who Receive Frequent Blood Transfusion
dc.typeArticle

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