Local allergic rhinitis - a narrative review

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dc.authoridBAYAR MULUK, NURAY/0000-0003-3602-9289
dc.contributor.authorManole, F.
dc.contributor.authorMuluk, N. Bayar
dc.contributor.authorOguz, O.
dc.contributor.authorUlusoy, S.
dc.contributor.authorScadding, G. K.
dc.contributor.authorProkopakis, E.
dc.contributor.authorKalogjera, L.
dc.date.accessioned2025-01-21T16:42:22Z
dc.date.available2025-01-21T16:42:22Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThis narrative review aims to provide an up-to-date definition of local allergic rhinitis (LAR), its classification, mechanisms, comorbidities, recommendations for diagnosis and treatment, and define needs in this area. Both 'PubMed' and 'Science Direct' literature was reviewed systematically, and a manual search for studies not previously encountered in the databases was also carried out. Published studies were identified in PubMed covering the period from 1947 to 2022. The following keyword search strategy was used: (local allergic rhinitis* OR entopy* OR local Immunoglobulin E * OR nasal specific Immunoglobulin E). LAR involves Type 2 nasal inflammation with local IgE and cannot be diagnosed by systemic methods, such as skin prick or blood IgE tests. A nasal allergen challenge is necessary for diagnosis. LAR can respond to usual AR treatments, including allergen specific immunotherapy (AIT). LAR is a novel entity that requires additional investigation in terms of prevalence, proper diagnosis, treatment, and prognosis. The target outcomes and possible benefits of this review are to achieve a consensus for the study and diagnosis of LAR and increase interest in this area.
dc.identifier.endpage1088
dc.identifier.issn1128-3602
dc.identifier.issue3
dc.identifier.pmid38375713
dc.identifier.startpage1077
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25064
dc.identifier.volume28
dc.identifier.wosWOS:001167990400003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherVerduci Publisher
dc.relation.ispartofEuropean Review For Medical and Pharmacological Sciences
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectKey Words; Atopy; Classification; Comorbidities; Local Al- lergic Rhinitis (LAR); Local IgE production; mech- anisms; Rhinitis; Specific Immunoglobulin E (IgE); Nasal provocation test (NPT)
dc.titleLocal allergic rhinitis - a narrative review
dc.typeReview Article

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