Systemic Immune-Inflammation Index and C-Reactive Protein/Albumin Ratio Could Predict Acute Stent Thrombosis and High SYNTAX Score in Acute Coronary Syndrome

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dc.authoridNURKOC, SERDAR GOKHAN/0000-0001-6575-9198
dc.authoridYALCIN, MEHMET RIDVAN/0000-0001-5585-1505
dc.authoridyakut, idris/0000-0002-3038-3829
dc.authoridAkboga, Mehmet Kadri/0000-0001-5498-2837
dc.authoridINANC, IBRAHIM HALIL/0000-0003-4046-6748
dc.contributor.authorAkboga, Mehmet Kadri
dc.contributor.authorInanc, Ibrahim Halil
dc.contributor.authorSabanoglu, Cengiz
dc.contributor.authorAkdi, Ahmet
dc.contributor.authorYakut, Idris
dc.contributor.authorYuksekkaya, Baran
dc.contributor.authorNurkoc, Serdar
dc.date.accessioned2025-01-21T16:44:50Z
dc.date.available2025-01-21T16:44:50Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAcute stent thrombosis (AST) is associated with increased morbidity and mortality. The main aim of this study was to evaluate the prognostic value of the systemic immune-inflammation index (SII) and C-reactive protein (CRP) to albumin ratio (CAR) in predicting AST and high SYNTAX score in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI). The criteria of the Academic Research Consortium were used to determine definite stent thrombosis. A total of 2077 consecutive patients with ACS undergoing PCI were retrospectively enrolled. Platelet, white blood cell and neutrophil counts, as well as SII, CRP, CAR, and peak cardiac troponin I (cTnI) values were significantly higher, whereas the lymphocyte count and albumin values were significantly lower in the AST (+) group compared with the AST (-) group (P < .05). SYNTAX score showed significant positive correlations with SII (r = .429, P < .001) and CRP (r = .402, P < .001). Multivariate logistic regression analysis showed that SII and CAR, as well as age, diabetes mellitus, stent length, and peak cTnI are independent predictors of AST and high SYNTAX score. In conclusion, the SII and CAR are simple, relatively cheap, and reliable inflammatory biomarkers that can predict AST and high SYNTAX scores in ACS.
dc.identifier.doi10.1177/00033197221125779
dc.identifier.endpage701
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.issue7
dc.identifier.pmid36069742
dc.identifier.startpage693
dc.identifier.urihttps://doi.org/10.1177/00033197221125779
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25523
dc.identifier.volume74
dc.identifier.wosWOS:000851303300001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSage Publications Inc
dc.relation.ispartofAngiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectacute coronary syndrome; biomarker; C-reactive protein to albumin ratio; systemic immune-inflammation index; stent thrombosis; SYNTAX score
dc.titleSystemic Immune-Inflammation Index and C-Reactive Protein/Albumin Ratio Could Predict Acute Stent Thrombosis and High SYNTAX Score in Acute Coronary Syndrome
dc.typeArticle

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