Design and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study

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dc.contributor.authorCelik, Oguzhan
dc.contributor.authorCil, Cem
dc.contributor.authorOzlek, Bulent
dc.contributor.authorOzlek, Eda
dc.contributor.authorDogan, Volkan
dc.contributor.authorBasaran, Ozcan
dc.contributor.authorDemirci, Erkan
dc.date.accessioned2025-01-21T16:37:21Z
dc.date.available2025-01-21T16:37:21Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: The aim of this study was to describe the current status of aspirin use and the demographic characteristics of patients on aspirin for primary and secondary prevention of cardiovascular diseases. Methods: The Appropriateness of Aspirin Use in Medical Outpatients: A Multicenter, Observational Study (ASSOS) trial was a multicenter, cross-sectional, and observational study conducted in Turkey. The study was planned to include 5000 patients from 14 cities in Turkey. The data were collected at one visit, and the current clinical practice regarding aspirin use was evaluated (ClinicalTrials.gov number NCT03387384). Results: The study enrolled all consecutive patients who were admitted to the outpatient cardiology clinics from March 2018 until June 2018. Patients should be at least 18 years old, have signed written informed consent, and on aspirin (80-325 mg) therapy within the last 30 days. Cardiologists from the hospital participates in the study. Patients were divided into 2 categories according to presence or absence of atherosclerotic cardiovascular disease, namely secondary prevention group and primary prevention group, respectively. The appropriate use of aspirin in the primary and secondary prevention groups was assessed according to the European Society of Cardiology guidelines and US Preventive Services Task Force. The patients' gastrointestinal bleeding risk factors and colorectal cancer risk were evaluated. Conclusion: The ASSOS registry will be the most comprehensive and largest study in Turkey evaluating the appropriateness of aspirin use. The results of this study help understand the potential misuse of aspirin in a real-world setting.
dc.identifier.doi10.14744/AnatolJCardiol.2018.47587
dc.identifier.endpage362
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue6
dc.identifier.pmid30504736
dc.identifier.startpage354
dc.identifier.urihttps://doi.org/10.14744/AnatolJCardiol.2018.47587
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24463
dc.identifier.volume20
dc.identifier.wosWOS:000456198000009
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectaspirin; primary prevention; outpatients; secondary prevention
dc.titleDesign and rationale for the ASSOS study: Appropriateness of aspirin use in medical outpatients a multicenter and observational study
dc.typeArticle

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