Association Between Plasma Adrenomedullin Levels and Bone Mineral Density in Patients with Polycystic Ovary Syndrome

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dc.contributor.authorUçar, Banu
dc.contributor.authorNoyan, Volkan
dc.contributor.authorYücel, Aykan
dc.contributor.authorSağsöz, Nevin
dc.contributor.authorÇağlayan, Osman
dc.date.accessioned2025-01-21T16:36:03Z
dc.date.available2025-01-21T16:36:03Z
dc.date.issued2005
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: The aim of the study was to compare bone mineral density measurements between patients with polycystic ovary syndrome (PCOS) and age and body mass index matched healthy controls, and to examine whether plasma adrenomedullin concentration was associated with bone mineral density. Design: Prospective study. Setting: Department of Obstetrics and Gynecology, Kirikkale University School of Medicine. Patients: Twenty women with PCOS and 13 healthy control subjects were enrolled in the study. Interventions: Plasma adrenomedullin, serum androstenedione, free testosterone, testosterone, DHEAS, SHBG, FSH, LH, estradiol, fasting insulin and fasting glucose were measured in each subject. Bone mineral density (lumbar spine 2-4 (L2-4), femoral neck, ward's triangle, great trochanter) measurements were measured using dual energy X-ray absorptiometry. Insulin resistance was estimated by fasting insulin level, fasting glucose: insulin ratio and 75 g of glucose tolerance test for 2 hours. Main Outcome Measures: Bone mineral density and correlation between bone mineral density and plasma adrenomedullin. Result: Bone mineral density measurements did not differ between the groups. There were no correlations between plasma adrenomedullin and bone mineral density measurements. Conclusions: Further studies are needed to evaluate the relation between bone mineral density and plasma adrenomedullin.
dc.identifier.endpage326
dc.identifier.issn2149-9322
dc.identifier.issn2149-9330
dc.identifier.issue4
dc.identifier.startpage321
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24242
dc.identifier.volume2
dc.identifier.wosWOS:000409139000011
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isotr
dc.publisherGalenos Yayincilik
dc.relation.ispartofTurkish Journal of Obstetrics and Gynecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectPolycystic ovary syndrome; adrenomedullin; bone mineral density
dc.titleAssociation Between Plasma Adrenomedullin Levels and Bone Mineral Density in Patients with Polycystic Ovary Syndrome
dc.typeArticle

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