LIPID PEROXIDATION AND THE ANTIOXIDANT CAPACITY OF DIALYSIS PATIENTS: The Effects of a Single Hemodialysis Session with Different Dialysis Membranes

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dc.authoridKulaksizoglu, Sevsen/0000-0002-7613-2240
dc.contributor.authorDerici, Ulver
dc.contributor.authorEbinc, Fatma Ayerden
dc.contributor.authorYilmaz, Murat
dc.contributor.authorKulaksizoglu, Sevsen
dc.contributor.authorArinsoy, Turgay
dc.contributor.authorSindel, Sukrur
dc.date.accessioned2025-01-21T16:42:21Z
dc.date.available2025-01-21T16:42:21Z
dc.date.issued2008
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: To estimate lipid peroxidation and the antioxidant defense capacity of dialysis patients and the effects of different types of dialysis membranes on these parameters. Methods: Fifty-four dialysis patients and 30 healthy controls were included in this study. Ten of the dialysis patients were on continuous ambulatory peritoneal dialysis treatment and the rest were on hemodialysis with either polycarbonate membrane (n=10) or hemophan membrane (n=34). Polycarbonate membranes were switched with a vitamin E-coated dialyzer in the subsequent dialysis session. Total antioxidant status and malondialdehyde levels were studied to determine the antioxidant defense capacity and lipid peroxidation, respectively, before and after the dialysis session. Results: Plasma total antioxidant status levels were lower (1.51 +/- 0.2 mmol/l vs. 1.75 +/- 0.20 mmol/l p<0.05) and malondialdehyde levels were higher (2.2 +/- 1.17 nmol/ml vs. 0.60 +/- 0.20 nmol/ml p<0.05) in all dialysis patients compared to the control group. After one hemodialysis session, there were no significant alterations in parameters for either type of dialysis membrane. Conclusion: All dialysis patients have an increased oxidative status. A single hemodialysis session with different dialysis membranes does not seem to significantly change the oxidant or antioxidant levels.
dc.identifier.endpage55
dc.identifier.issn2147-2092
dc.identifier.issue2
dc.identifier.startpage53
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25061
dc.identifier.volume19
dc.identifier.wosWOS:000217434600001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherGazi Univ, Fac Med
dc.relation.ispartofGazi Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectantioxidant status; malondialdehyde; hemodialysis; peritoneal dialysis
dc.titleLIPID PEROXIDATION AND THE ANTIOXIDANT CAPACITY OF DIALYSIS PATIENTS: The Effects of a Single Hemodialysis Session with Different Dialysis Membranes
dc.typeArticle

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