Can Routine Blood Biochemistry Parameters be Predictive Prognostic Marker(s) in Operated Patients with Meningioma WHO Grade 1?

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dc.authoridOzdemir, Alemiddin/0000-0002-5431-7287
dc.authoridBAKAR, BULENT/0000-0002-6236-7647
dc.contributor.authorYuksel, Ulas
dc.contributor.authorOzdemir, Alemiddin
dc.contributor.authorKisa, Ucler
dc.contributor.authorOgden, Mustafa
dc.contributor.authorBakar, Bulent
dc.date.accessioned2025-01-21T16:36:18Z
dc.date.available2025-01-21T16:36:18Z
dc.date.issued2021
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground Today, there is a need for new and independent additional advanced markers that can predict the prognosis of meningioma patients, postoperatively. The present study aimed to find out postoperative short-term prognostic markers in patients with meningioma using their demographic data and routine blood biochemistry findings evaluated preoperatively. Methods The Glasgow Coma Scale (GCS), and Glasgow Outcome Scale (GOS) scores of the patients were recorded. Additionally, preoperatively obtained serum glucose, C-reactive protein (CRP), sodium, potassium, creatinine, blood urea nitrogen, aspartate aminotransferase (AST), alanine aminotransferase, and hemoglobin level values, platelet, leukocyte, neutrophil, lymphocyte, eosinophil, basophil, and monocyte count results, erythrocyte sedimentation rate (ESR), neutrophil-lymphocyte ratio, platelet-lymphocyte ratio (PLR) and lymphocyte-monocyte ratio (LMR) values were evaluated. Results In the present study, 23 operated patients with meningioma World Health Organization (WHO) grade 1 (17 females, 6 males) were included. Correlation test results revealed that the GCS score, platelet count, and serum potassium level values could directly predict the short-term prognosis of these patients. Additionally, these test results suggested that the lymphocyte, monocyte, and eosinophil count values, PLR, LMR, ESR, serum glucose, CRP, and AST level values could be indirect markers in predicting the short-term prognosis. However, likelihood ratio test results revealed that only monocyte count value, LMR value, and serum CRP level value could be the markers for prediction of the short-term prognosis. Conclusion At the end of the present study, it was concluded that the monocyte count value, LMR value, and serum CRP level value could be the best markers in predicting the short-term prognosis of the operated meningioma patients.
dc.identifier.doi10.1055/s-0040-1722246
dc.identifier.endpageE145
dc.identifier.issn0103-5355
dc.identifier.issn2359-5922
dc.identifier.issue2
dc.identifier.startpageE137
dc.identifier.urihttps://doi.org/10.1055/s-0040-1722246
dc.identifier.urihttps://hdl.handle.net/20.500.12587/24293
dc.identifier.volume40
dc.identifier.wosWOS:000608440800002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherGeorg Thieme Verlag Kg
dc.relation.ispartofBrazilian Neurosurgery-Arquivos Brasileiros De Neurocirurgia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectbiochemistry; biomarker; meningioma; prognosis
dc.titleCan Routine Blood Biochemistry Parameters be Predictive Prognostic Marker(s) in Operated Patients with Meningioma WHO Grade 1?
dc.typeArticle

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