Laser Therapy in Knee Osteoarthritis: An Experimental Study

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dc.contributor.authorOzbay, Kadri Koray
dc.contributor.authorAtalar, Ebru
dc.contributor.authorKarahan, Siyami
dc.contributor.authorOrkun, Sevim
dc.contributor.authorIde, Tayfun
dc.contributor.authorTugcu, Ilknur
dc.contributor.authorSezer, Refia
dc.date.accessioned2025-01-21T16:42:18Z
dc.date.available2025-01-21T16:42:18Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: In this study, it is aimed to examine the effects of Infrared Gallium-Arsenic (Ga-Ar) laser therapy in rat osteoarthritis (OA) model that is formed chemically on the knee joint cartilage. Material and methods: Fifty-six female Wistar Albino rats having weights between 250 and 300 grams were used and the rats were divided in 3 groups. Group 1 and group 2 are the control (C) groups. In group 1 (C-1), 0.9% saline solution was aplied to the left knee joint of 32 rats and in group 2 (C-2), 1 mg monoiodoacetate (MIA) is applied to the right knee joint of the same 32 rats. Group 3 is the experimental (E) group and in this group, 1 mg MIA application to the right knees of 24 rats. Ga-Ar laser therapy was started after 24 hours for group 3 and it was applied for 15 days with 24-hour intervals. In all 3 groups, knee bending test was applied daily. Euthanasia was applied on 1st,7th and 15th days to 8 rats in C-1 and C-2 and on 7th, 15th and 30th days to 8 rats in group E. Their knee joints were removed, and they were histopathologically assessed under a light microscope. Results: As a result of the statistical assessment, in the assessment between the total scores between C-1 and C-2 groups, scores of the C-2 group were found higher at all the time points (p=0.001, p=0.002). Also when the E and C-2 groups were compared, no statistically significant difference was observed (p>0.05). There was no correlation between the pain assessment of knee bending test and the level of histopathological findings. Conclusions: We found no effect of laser therapy in the treatment of early knee osteoarthritis.
dc.identifier.doi10.12996/gmj.2022.31
dc.identifier.endpage133
dc.identifier.issn2147-2092
dc.identifier.issue2
dc.identifier.scopus2-s2.0-85129275625
dc.identifier.scopusqualityQ4
dc.identifier.startpage129
dc.identifier.urihttps://doi.org/10.12996/gmj.2022.31
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25047
dc.identifier.volume33
dc.identifier.wosWOS:000773358500003
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherGazi Univ, Fac Med
dc.relation.ispartofGazi Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectOsteoarthritis; rats; wistar; laser therapy; knee joint
dc.titleLaser Therapy in Knee Osteoarthritis: An Experimental Study
dc.typeArticle

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