Risk Factors for Intracranial Aneurysm Rupture: A Clinical Case Series and Systematic Review of the Literature

dc.contributor.authorCelikoglu, Erhan
dc.contributor.authorEksi, Murat Sakir
dc.contributor.authorBastaci, Feryal
dc.contributor.authorHazneci, Julide
dc.contributor.authorBorekci, Ali
dc.contributor.authorTopal, Arif
dc.contributor.authorSelahi, Ozge
dc.date.accessioned2025-01-21T16:44:17Z
dc.date.available2025-01-21T16:44:17Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAIM: To evaluate the patients who underwent surgery for an anterior communicating artery (AcomA) aneurysm at our institution. We analyzed our case series and systematically reviewed the literature to identify factors that could predict the rupture of an intracranial aneurysm in patients with AcomA aneurysms or any intracranial aneurysm. MATERIAL and METHODS: We conducted a cross-sectional analysis of prospectively collected data from patients who underwent surgery for AcomA aneurysms at a single institution between January 2014 and May 2023. Predictors for the rupture of intracranial aneurysm were systematically reviewed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines and the Pubmed and MEDLINE databases. RESULTS: Younger age (odds ratio (OR): 0.957, 95% confidence interval (CI): 0.920-0.995, p=0.028), presence of a daughter sac (OR: 3.209, 95% CI: 1.095-9.408, p=0.034), and ever-smoking (OR: 0.357, 95% CI: 0.137-0.930, p=0.035) were significant predictors of increased risk of rupture in patients with AcomA aneurysms. Several aneurysm- and patient-related risk factors for rupture of intracranial aneurysms were retrieved via the literature analysis. CONCLUSION: Younger age, ever-smoking, and presence of a daughter sac increased the risk of AcomA aneurysm rupture. A systematic literature review revealed several more aneurysm- and patient-related risk factors for rupture of the intracranial aneurysms. Our results could aid neurosurgeons during their decision-making process when treating patients with unruptured intracranial aneurysms.
dc.description.sponsorshipWe send our condolences for the loss of Juha Hernesniemi, who opened the doors of intracranial vascular neurosurgery, treated many patients and trained many neurosurgeons. He has become a legendary vascular neurosurgeon and idol for many of us. We dedicated this manuscript to his memory.
dc.identifier.doi10.5137/1019-5149.JTN.44866-23.2
dc.identifier.endpage639
dc.identifier.issn1019-5149
dc.identifier.issue4
dc.identifier.pmid37528725
dc.identifier.startpage624
dc.identifier.urihttps://doi.org/10.5137/1019-5149.JTN.44866-23.2
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25410
dc.identifier.volume34
dc.identifier.wosWOS:001263093400010
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherTurkish Neurosurgical Soc
dc.relation.ispartofTurkish Neurosurgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectAneurysm; Rupture; Subarachnoid hemorrhage; Risk factor; Anterior communicating; unruptured
dc.titleRisk Factors for Intracranial Aneurysm Rupture: A Clinical Case Series and Systematic Review of the Literature
dc.typeReview Article

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