Use of SAFARI 2n° as workhorse wire for left-sided structural heart interventions

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dc.contributor.authorInanc, Ibrahim H.
dc.contributor.authorMutlu, Deniz
dc.contributor.authorMarmagkiolis, Kostas
dc.contributor.authorIliescu, Cezar
dc.contributor.authorAtes, Ismail
dc.contributor.authorCilingiroglu, Mehmet
dc.date.accessioned2025-01-21T16:55:49Z
dc.date.available2025-01-21T16:55:49Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: With the advances in percutaneous treatment technologies, the left atrial appendage occlusion (LAAO) and the transcatheter mitral valve repair using MitraClip (TMVR) are increasingly being performed today. The SAFARI 2n degrees guidewire is primarily used during transcatheter aortic valve implantation (TAVI), our group has also been using it during MitraClip and LAAO procedures. Our clinical study aimed to share our data on the safety and effectiveness for the use of the SAFARI 2n degrees guidewire during MitraClip or LAAO procedures. Methods: This study included a total of 1730 patients (948 patients of MitraClip and 782 of LAAO). It was designed as single arm, retrospective, and multicenter between July 2016 and August 2022. SAFARI 2n degrees guidewire was used exclusively during all the procedures. Results: A total of 1730 patients (male 55.8 %) were included in the study. There was no guidewire-related complications, stroke/transient ischemic attack, bleeding (minor/major/life-threatening), need for cardiac surgery, pneumonia, and vascular dissection/rupture in patients undergoing LAAO. There were 2 device-related pericardial effusions without tamponade. No stroke/transient ischemic attack, bleeding (minor/major/life-threatening), mortality, need for cardiac surgery, pneumonia, guidewire-related complication, pericardial effusion, vascular dissection/rupture, or clip embolization was observed in patients undergoing MitraClip. Conclusions: By taking advantage of its pre-shaped structure, the SAFARI 2n degrees guidewire seems to offer a reliable and safe device delivery for both MitraClip and LAAO procedures as a regular work horse wire. Our results should be confirmed by larger randomized or prospective trials.
dc.identifier.doi10.1016/j.carrev.2024.02.003
dc.identifier.endpage24
dc.identifier.issn1553-8389
dc.identifier.issn1878-0938
dc.identifier.pmid38388247
dc.identifier.startpage21
dc.identifier.urihttps://doi.org/10.1016/j.carrev.2024.02.003
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25849
dc.identifier.volume64
dc.identifier.wosWOS:001257709200001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherElsevier Inc
dc.relation.ispartofCardiovascular Revascularization Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectLeft atrial appendage occlusion; Transcatheter mitral valve repair; SAFARI 2n degrees guidewire
dc.titleUse of SAFARI 2n° as workhorse wire for left-sided structural heart interventions
dc.typeArticle

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