Impact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multi?center study

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dc.contributor.authorGok, Kevser
dc.contributor.authorNas, Kemal
dc.contributor.authorTekeoglu, Ibrahim
dc.contributor.authorSunar, Ismihan
dc.contributor.authorKeskin, Yasar
dc.contributor.authorKilic, Erkan
dc.contributor.authorSargin, Betul
dc.date.accessioned2025-01-21T16:27:44Z
dc.date.available2025-01-21T16:27:44Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractThis article aims to evaluate the possible effect of obesity on quality of life, psychological status, and other clinical variables in Psoriatic arthritis (PsA). PsA patients have been recruited by the Turkish League Against Rheumatism-Network from various centers in Turkey in this cross-sectional study. Patients with a body mass index (BMI) ? of 30 kg/m2 were considered obese. Differences among patients with regard to obesity status were assessed with health-related quality of life measures (PsA Quality of Life Questionnaire [PsAQoL]), psychological status (Hospital Anxiety and Depression Scale [HADS]), and disease activity parameters (the Disease Activity index for PSoriatic Arthritis [DAPSA], Disease Activity Score 28-C-reactive protein [DAS28-CRP], Bath Ankylosing Spondylitis Disease Activity Index [BASDAI], Psoriasis Area and Severity Index [PASI]), physical functions (Ankylosing Spondylitis Functional Index [BASFI], Health Assessment Questionnaire [HAQ], and Health Assessment Questionnaire for the spondyloarthropathies [HAQ-S]). Pain was assessed using visual analog scale of pain (VAS-P), and fatigue was evaluated using visual analog scale of fatigue (VAS-F) and Functional Assessment of Chronic Illness Therapy (FACIT). A total of 1033 patients with PsA, 650 (62.9%) non-obese and 383 (37.1%) obese were included in the study. The PsAQoL, HADS-Anxiety, HADS-Depression, DAPSA, DAS28-CRP, BASDAI, BASFI, HAQ and HAQ-S scores of the obese group were higher than the non-obese group (p < 0.05). VAS-P and PASI scores were similar between group of patients with and without obesity. Obese patients had higher median scores of VAS-F and FACIT than non-obese patients (p < 0.05). Linear regression analysis showed that BMI affects the quality of life, depression, and disease activity. Consequently, obesity has significant associations with higher disease activity, lower QoL, risk of anxiety, depression, and fatigue. Therefore, obesity should also be taken into account in the management of PsA patients. © 2021, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
dc.identifier.doi10.1007/s00296-021-04971-8
dc.identifier.endpage668
dc.identifier.issn0172-8172
dc.identifier.issue4
dc.identifier.pmid34453579
dc.identifier.scopus2-s2.0-85113804909
dc.identifier.scopusqualityQ1
dc.identifier.startpage659
dc.identifier.urihttps://doi.org/10.1007/s00296-021-04971-8
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23411
dc.identifier.volume42
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer Science and Business Media Deutschland GmbH
dc.relation.ispartofRheumatology International
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectAnxiety; Depression; Disease activity; Obesity; Psoriatic arthritis; Quality of life
dc.titleImpact of obesity on quality of life, psychological status, and disease activity in psoriatic arthritis: a multi?center study
dc.typeArticle

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