The evaluation of Qtc interval, Qtc dispersion, dysrhythmia and heart rate variability undergoing sevoflurane and desflurane anesthesia in laporoscopic surgery

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dc.contributor.authorKaymak, Çetin
dc.contributor.authorDoğru, T.
dc.contributor.authorBaşar, Hülya
dc.date.accessioned2020-06-25T15:13:57Z
dc.date.available2020-06-25T15:13:57Z
dc.date.issued2007
dc.departmentKırıkkale Üniversitesi
dc.description.abstractIntroduction: The aim of the present study was to asses the effects of sevoflurane and desflurane as inhalational anaesthetics on heart rate variability, dysrhythmias, QT interval and QT dispersion in patients who will undergo laporoscopic cholecystectomy under general anaesthesia. Material and Methods: 34 patients who will undergo elective laparoscopic cholecystectomy are enrolled in the study. The patients were monitored with Holter device 15 minutes before the anaesthesia induction till 30 minutes in recovery room. Anaesthesia was induced using 4-7 mg kg-1 thiopental sodium, l ?g kg -1 fentanyl and 1 mg kg-1 vecuronium for muscle relaxation. Cases were randomized into 2 groups; Group 1 Sevoflurane, Croup 2 Desflurane. End tidal CO2, O2, N2O were monitorized and ventilation were maintained to Keep EtCO2 between 30-40 mmHg. Minimum, maximum, mean heart rates and heart rate variability parameters included low frequency (LF), high frequency (HF) values which are heart rate variability Parameters, LF/HF ratio, Global Sympathetic Index (GSI), R-R intervals were measured in preoperative, intraoperative periods and 2 nd, 10th and 30th minutes after extubation. Atrial and ventricular dysrhythmias (AES, VES) were determined. QT interval was corrected using Bazett's formula (QTc=QT?RR). QT dispersion was calculated by finding shortest and longest QT interval. Results: Assessing data from Holter Monitor maximum heart rates values were significantly higher in Desflurane group (p=0.049). LF/HF ratio, GSI values were higher in Desflurane group in perioperative period except in induction-extubation events. Maximum R-R intervals in Sovoflurane group in perioperative period were significantly higher. In desflurane group QT intervals were significantly longer and QT dispersion was significantly more frequent. Positive correlation between sympathetic tonus increase and YES was recognized in both groups. Conclusion: In this study sympathetic activation was frequently seen in desflurane group, Severe dysrhythmias did not occur in both groups. Although both desflurane and sevoflurane increased the rate of QT, the increased of QTc and QTd in desflurane anesthesia were significantly higher than sevoflurane anesthesia.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.endpage63en_US
dc.identifier.issn13040871
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-34248652111
dc.identifier.scopusqualityN/A
dc.identifier.startpage57en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1983
dc.identifier.volume35en_US
dc.indekslendigikaynakScopus
dc.language.isotr
dc.relation.ispartofTurk Anesteziyoloji ve Reanimasyon Dernegi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDesfluraneen_US
dc.subjectGeneral anaesthesiaen_US
dc.subjectHeart rate variabilityen_US
dc.subjectQT dispersionen_US
dc.subjectQTc intervalen_US
dc.subjectSevofluraneen_US
dc.titleThe evaluation of Qtc interval, Qtc dispersion, dysrhythmia and heart rate variability undergoing sevoflurane and desflurane anesthesia in laporoscopic surgeryen_US
dc.title.alternativeLaparoskopik kolesistektomi cerrahisinde sevofluran ve desfluran anestezisinin Qtc intervali, QT dispersiyonu, aritmi oluşumu ve kalp hizi değişkenliği üzerine etkisien_US
dc.typeArticle

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