Changes in the size distribution of goat steroidogenic luteal cells during pregnancy

dc.contributor.authorArikan, S
dc.contributor.authorYigit, AA
dc.date.accessioned2020-06-25T17:35:34Z
dc.date.available2020-06-25T17:35:34Z
dc.date.issued2003
dc.departmentKırıkkale Üniversitesi
dc.description.abstractExperiments were conducted to investigate the size distribution of goat steroidogenic luteal cells throughout pregnancy. Corpora lutea were collected from very early (<6 weeks), early (6-8 weeks), middle (9-14 weeks) or late (15-18 weeks) stages of pregnancy. Luteal tissue was dissociated into single-cell suspension by enzyme treatments. Cells were stained for 3beta-hydroxysteroid dehydrogenase (3beta-HSD) activity, a marker for steroidogenic cells. The steroidogenic cells covered a wide spectrum of size ranging from 5 to 45 mum in diameter. There was a significant increase in mean cell diameter (P > 0.01) as pregnancy progressed. Mean diameter of 3beta-HSD positive cells increased from 14.73 +/- 0.35 mum in the corpus luteum of very early pregnancy to 24.20 +/- 0.45 mum in the corpus luteum of late pregnancy. The ratio of large (>20 mum in diameter) to small (5-20 mum in diameter) luteal cells was 0.28:1.0 in very early pregnancy, with the 7.5-15 mum cell size class being dominant. However, the ratio of large-to-small luteal cells was increased to 1.77:1.0 mum as pregnancy advanced and 25-35 mum cell sizes became predominant. It is likely that small luteal cells could develop into large cells as pregnancy progresses. Development of pregnancy is also associated with an increase in size of steroidogenic luteal cells. (C) 2002 Elsevier Science B.V. All rights reserved.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/S0921-4488(02)00261-4
dc.identifier.endpage231en_US
dc.identifier.issn0921-4488
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-0037369298
dc.identifier.scopusqualityQ2
dc.identifier.startpage227en_US
dc.identifier.urihttps://doi.org/10.1016/S0921-4488(02)00261-4
dc.identifier.urihttps://hdl.handle.net/20.500.12587/3154
dc.identifier.volume47en_US
dc.identifier.wosWOS:000181212200007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Bven_US
dc.relation.ispartofSmall Ruminant Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectgoaten_US
dc.subjectcorpus luteumen_US
dc.subject3 beta-HSDen_US
dc.subjectluteal cellsen_US
dc.subjectpregnancyen_US
dc.titleChanges in the size distribution of goat steroidogenic luteal cells during pregnancyen_US
dc.typeArticle

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