Hypoglycemic activity of a dietary mushroom Pleurotus florida on alloxan induced diabetic rats

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dc.contributor.authorKhatun, Selima
dc.contributor.authorIslam, Aminul
dc.contributor.authorGüler, Perihan
dc.contributor.authorÇakılcıoğlu, Uğur
dc.contributor.authorChatterjee, C. Narayan
dc.date.accessioned2020-06-25T14:47:04Z
dc.date.available2020-06-25T14:47:04Z
dc.date.issued2013
dc.departmentKırıkkale Üniversitesi
dc.description.abstractSpecies of Pleurotus possess various medicinal properties including hypoglycemic and hypocholesterolemic activities. The feeding effect of the mushroom Pleurotus florida in powdered form was evaluated on growth, blood glucose and cholesterol level in alloxan-induced diabetic albino rats against control. The starch was estimated in dry mushroom and found to be 0.28% (dry weight). The result indicated no significant difference in respect of gaining body weights between Bengal gram-fed and mushroom-fed groups. For studying antidiabetic effect, the control group and half of alloxan-induced (100 mg/kg i.p) experimental groups were fed on normal diet with Bengal gram whereas the other half of alloxan-induced group was fed on same diet but with additional mushroom powder. Blood samples were analysed for glucose, serum cholesterol, triglycerides and uric acid levels on 7th, 14th, 21st and 28th days of alloxan treatment. Body weights and mortality were noted during the period of study. The diabetic group administered with mushroom diet showed significantly decreased level of blood glucose and cholesterol compared to the counterpart. Estimation of lipid profile revealed much lower LDL cholesterol in mushroom fed diabetic group than in non- mushroom fed diabetic control group. The study, thus, points out the prominent effect of feeding dried mushroom (P. florida) on growth of albino rat and positive effect of P. florida on lowering blood glucose and cholesterol level in diabetic rats thereby suggesting its hypoglycemic and hypocholesterolemic effect.en_US
dc.description.abstractSpecies of Pleurotus possess various medicinal properties including hypoglycemic and hypocholesterolemic activities. The feeding effect of the mushroom Pleurotus florida in powdered form was evaluated on growth, blood glucose and cholesterol level in alloxan-induced diabetic albino rats against control. The starch was estimated in dry mushroom and found to be 0.28% (dry weight). The result indicated no significant difference in respect of gaining body weights between Bengal gram-fed and mushroom-fed groups. For studying antidiabetic effect, the control group and half of alloxan-induced (100 mg/kg i.p) experimental groups were fed on normal diet with Bengal gram whereas the other half of alloxan-induced group was fed on same diet but with additional mushroom powder. Blood samples were analysed for glucose, serum cholesterol, triglycerides and uric acid levels on 7th, 14th, 21st and 28th days of alloxan treatment. Body weights and mortality were noted during the period of study. The diabetic group administered with mushroom diet showed significantly decreased level of blood glucose and cholesterol compared to the counterpart. Estimation of lipid profile revealed much lower LDL cholesterol in mushroom fed diabetic group than in non- mushroom fed diabetic control group. The study, thus, points out the prominent effect of feeding dried mushroom (P. florida) on growth of albino rat and positive effect of P. florida on lowering blood glucose and cholesterol level in diabetic rats thereby suggesting its hypoglycemic and hypocholesterolemic effect.en_US
dc.identifier.citationKhatun, S., İslam, A., Güler, P., Çakılcıoğlu, U., Chatterjee, C. N. (2013). Hypoglycemic activity of a dietary mushroom Pleurotus florida on alloxan induced diabetic rats. Biological Diversity and Conservation, 6(2), 91 - 96.en_US
dc.identifier.endpage96en_US
dc.identifier.issn1308-5301
dc.identifier.issn1308-8084
dc.identifier.issue2en_US
dc.identifier.startpage91en_US
dc.identifier.trdizinid148334
dc.identifier.urihttps://app.trdizin.gov.tr/publication/paper/detail/TVRRNE16TTBOQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1549
dc.identifier.volume6en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofBiological Diversity and Conservation
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiyolojien_US
dc.titleHypoglycemic activity of a dietary mushroom Pleurotus florida on alloxan induced diabetic ratsen_US
dc.typeArticle

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