Plasma antioxidant enzyme levels in smoker and non-smoker pregnant women and their correlation with uterine arterial doppler parameters
dc.contributor.author | Celikel O.O. | |
dc.contributor.author | Noyan V. | |
dc.contributor.author | Caglayan O. | |
dc.date.accessioned | 2020-06-25T15:18:03Z | |
dc.date.available | 2020-06-25T15:18:03Z | |
dc.date.issued | 2018 | |
dc.department | Kırıkkale Üniversitesi | |
dc.description.abstract | Introduction: Cigarettes contain many free radicals and cause oxidative stress in the body. Its contents decrease blood fluidity and blood stream by affecting the vascular endothelium; further, they directly or indirectly impair placental perfusion. Material and method: Catalase (CAT), malondialdehyde (MDA) and total sulfhydryl (SH) levels were analysed in venous blood specimens obtained from 49 smoker and 35 non-smoker pregnant women (age, 18-35 y) who were in the second trimester. Uterine arterial Doppler ultrasonography was performed to evaluate uterine perfusion. Pulsatile index (PI), resistance index (RI) and systole/diastole ratio (S/D) was measured. The smoker group was further subdivided into two groups: 1. those who smoked for <5 y and 2. Those who smoked for >5 y. Obtained data were analysed using the SPSS 11 statistical programme. Results: No significant differences were observed between the smoker and non-smoker groups in terms of demographic parameters and right–left uterine arterial Doppler parameters. The mean S/D ratio was significantly higher in the smoker group (P=0.01). The mean PI, mean RI and plasma MDA, CAT and total SH levels were similar in both groups. Although not statistically significant, the mean PI, RI and S/D ratio values of the smoker pregnant women who smoked for ? 5 y was found to be higher than of those who smoked for <5 y. Conclusion: There is no correlation between plasma antioxidant enzyme levels and uterine artery Doppler parameters; however, the duration of smoking may affect uterine perfusion. © 2018, Scientific Publishers of India. All rights reserved. | en_US |
dc.identifier.doi | 10.4066/biomedicalresearch.29-18-1082 | |
dc.identifier.endpage | 3700 | en_US |
dc.identifier.issn | 0970938X | |
dc.identifier.issue | 20 | en_US |
dc.identifier.scopus | 2-s2.0-85059120781 | |
dc.identifier.scopusquality | N/A | |
dc.identifier.startpage | 3697 | en_US |
dc.identifier.uri | https://doi.org/10.4066/biomedicalresearch.29-18-1082 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12587/2608 | |
dc.identifier.volume | 29 | en_US |
dc.indekslendigikaynak | Scopus | |
dc.language.iso | en | |
dc.publisher | Scientific Publishers of India | en_US |
dc.relation.ispartof | Biomedical Research (India) | |
dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Cigarette | en_US |
dc.subject | Oxidative stress | en_US |
dc.subject | Pregnancy | en_US |
dc.subject | Uterine artery | en_US |
dc.title | Plasma antioxidant enzyme levels in smoker and non-smoker pregnant women and their correlation with uterine arterial doppler parameters | en_US |
dc.type | Article |