Relapsing polychondritis misdiagnosed and treated as a “soft tissue infection” and a brief review of diagnostic clinical clues

dc.contributor.authorGündüz Ö.
dc.contributor.authorDemirkan S.
dc.contributor.authorSamav G.
dc.contributor.authorArslan H.
dc.contributor.authorÇakartaş R.
dc.date.accessioned2020-06-25T15:17:49Z
dc.date.available2020-06-25T15:17:49Z
dc.date.issued2017
dc.departmentKırıkkale Üniversitesi
dc.description.abstractRelapsing polychondritis (RPC) is a rare immune-mediated disease, which targets particularly the cartilaginous tissue. At the initial stages of RPC, recurring mild-inflammatory attacks targeting the ears, nose, eyes, joints and respiratory tract can be observed but as the disease progresses, aortic and/or mitral valvular regurgitation (AR/MR) or life-threatening tracheobronchomalacia (due to involvement of aortic, mitral valves and/or trachea) may occur, as well as severe destruction of the ear, nose, etc. RPC may coexist with other diseases, such as systemic vasculitides, Graves disease or myelodysplastic syndrome. Establishing an early diagnosis is of utmost importance to prevent the development of AR/MR, or tracheobronchomalacia by preserving the cartilage tissue and also to diagnose a possible coexisting disease. Patients, particularly at the initial stages of the disease may object to a skin biopsy due to concerns for visible scars. Therefore, a good grasp of RPC's clinical symptoms may facilitate to establish an early diagnosis. Copyright © 2017 by Türkiye Klinikleri.en_US
dc.identifier.doi10.5336/dermato.2017-58604
dc.identifier.endpage146en_US
dc.identifier.issn13000330
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85046116787
dc.identifier.scopusqualityQ4
dc.identifier.startpage142en_US
dc.identifier.urihttps://doi.org/10.5336/dermato.2017-58604
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2538
dc.identifier.volume27en_US
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherOrtadogŸu Reklam Tanitim Yayincilik Turizm Egitim Insaat Sanayi ve Ticaret A.S.en_US
dc.relation.ispartofTurkiye Klinikleri Dermatoloji
dc.relation.publicationcategoryDiğeren_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDiagnosisen_US
dc.subjectDiagnosisen_US
dc.subjectDifferentialen_US
dc.subjectOtitis externaen_US
dc.subjectPolychondritisen_US
dc.subjectRelapsingen_US
dc.titleRelapsing polychondritis misdiagnosed and treated as a “soft tissue infection” and a brief review of diagnostic clinical cluesen_US
dc.typeReview Article

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