Is there a relationship between serum kisspeptin levels and endometrial polyps in women with premenopausal status

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dc.contributor.authorYıldırım, Engin
dc.contributor.authorDerici, Mehmet Kürşat
dc.contributor.authorSimsek, Omer Yavuz
dc.contributor.authorDemir, Emre
dc.date.accessioned2020-06-25T14:47:13Z
dc.date.available2020-06-25T14:47:13Z
dc.date.issued2019
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: Endometrial polyps are frequently associated with abnormal uterine bleeding. The kispeptin family is one of the peptidesthat play a role in reproductive functions and whose expression varies in various uterine pathologies. The aim of the study was todetermine the relationship between serum Kisspeptin levels and endometrial polyps in women with premenopausal status.Material and Methods: The blood was collected prior to endometrial sampling from women admitted to the hospital due to abnormaluterine bleeding. According to the pathology results, patients were identified as polyp group (n38) (endometrial polyps) and controlgroup (n50) (normal endometrial findings). Kisspeptin-54 levels were determined by ELISA method from serum obtained fromvenous blood.Results: There were no difference was found between the patients’ age, body mass index, gravida, para, abortus and the numberof living children were compared (p0.05). There was no statistically significant difference between the groups in terms of folliclestimulating hormone, luteinizing hormone and thyroid stimulating hormone values (p0.05). Plasma kisspeptin (1.840.93 ng/dLand 1.320.47 ng/dL, p 0.008) and estradiol (90.3413.02 pg/mL and 81.7512.36 pg/mL, p0.002) levels were significantly higherin the polyp group than in the control group. After the Receiver Operating Characteristic (ROC) analysis the area under the curve(AUC) was 1.26 (p 0.08), (95% CI, 0.550-0.782). The sensitivity value was 0.684 (0.512-0.819), the specificity was 0.620 (0.471-0.750).Conclusion: The serum Kisspeptin-54 and estradiol levels were found higher in patients with endometrial polyps.en_US
dc.identifier.citationYıldırım, E., Derici, M. K., Şimşek, O. Y., Demir, E. (2019). Is there a relationship between serum kisspeptin levels and endometrial polyps in women with premenopausal status. Annals of Medical Research, 26(7), 1253 - 1257.en_US
dc.identifier.doi10.5455/annalsmedres.2019.04.216
dc.identifier.endpage1257en_US
dc.identifier.issn2636-7688
dc.identifier.issn2636-7688
dc.identifier.issue7en_US
dc.identifier.startpage1253en_US
dc.identifier.trdizinid317012
dc.identifier.urihttps://doi.org/10.5455/annalsmedres.2019.04.216
dc.identifier.urihttps://app.trdizin.gov.tr/publication/paper/detail/TXpFM01ERXlNZz09
dc.identifier.urihttps://hdl.handle.net/20.500.12587/1581
dc.identifier.volume26en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofAnnals of Medical Research
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiyolojien_US
dc.subjectDiş Hekimliğien_US
dc.subjectAlerjien_US
dc.subjectAnatomi ve Morfolojien_US
dc.subjectAndrolojien_US
dc.subjectAnestezien_US
dc.subjectOdyoloji ve Konuşma-Dil Patolojisien_US
dc.subjectBiyokimya ve Moleküler Biyolojien_US
dc.subjectBiyofiziken_US
dc.subjectBiyoteknoloji ve Uygulamalı Mikrobiyolojien_US
dc.subjectKalp ve Kalp Damar Sistemien_US
dc.subjectHücre Biyolojisien_US
dc.subjectKlinik Nörolojien_US
dc.subjectYoğun Bakım, Tıpen_US
dc.subjectDermatolojien_US
dc.subjectAcil Tıpen_US
dc.subjectEndokrinoloji ve Metabolizmaen_US
dc.subjectGastroenteroloji ve Hepatolojien_US
dc.subjectGeriatri ve Gerontolojien_US
dc.subjectSağlık Bilimleri ve Hizmetlerien_US
dc.subjectHematolojien_US
dc.subjectİmmünolojien_US
dc.subjectEnfeksiyon Hastalıklarıen_US
dc.subjectTamamlayıcı ve Entegre Tıpen_US
dc.subjectTıbbi Etiken_US
dc.subjectTıbbi İnformatiken_US
dc.subjectTıbbi Laboratuar Teknolojisien_US
dc.subjectGenel ve Dahili Tıpen_US
dc.subjectAdli Tıpen_US
dc.subjectTıbbi Araştırmalar Deneyselen_US
dc.subjectMikrobiyolojien_US
dc.subjectNörolojik Bilimleren_US
dc.subjectKadın Hastalıkları ve Doğumen_US
dc.subjectOnkolojien_US
dc.subjectGöz Hastalıklarıen_US
dc.subjectOrtopedien_US
dc.subjectKulak, Burun, Boğazen_US
dc.subjectPatolojien_US
dc.subjectPediatrien_US
dc.subjectPeriferik Damar Hastalıklarıen_US
dc.subjectFizyolojien_US
dc.subjectTemel Sağlık Hizmetlerien_US
dc.subjectPsikiyatrien_US
dc.subjectHalk ve Çevre Sağlığıen_US
dc.subjectRadyoloji, Nükleer Tıp, Tıbbi Görüntülemeen_US
dc.subjectRehabilitasyonen_US
dc.subjectSolunum Sistemien_US
dc.subjectRomatolojien_US
dc.subjectSpor Bilimlerien_US
dc.subjectCerrahien_US
dc.subjectTransplantasyonen_US
dc.subjectTropik Tıpen_US
dc.subjectÜroloji ve Nefrolojien_US
dc.subjectFarmakoloji ve Eczacılıken_US
dc.subjectToksikolojien_US
dc.titleIs there a relationship between serum kisspeptin levels and endometrial polyps in women with premenopausal statusen_US
dc.typeArticle

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