Predictors of Severity of Coronary Artery Disease in Patients with Acute ST-elevation Myocardial Infarction

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dc.authoridAlp, Caglar/0000-0001-5984-1857
dc.contributor.authorKaradeniz, Muhammed
dc.contributor.authorAydin, Cihan
dc.contributor.authorDemirkiran, Aykut
dc.contributor.authorAlp, Caglar
dc.date.accessioned2025-01-21T16:34:14Z
dc.date.available2025-01-21T16:34:14Z
dc.date.issued2024
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: Our study aims to investigate the relationship between platelet-lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), and the correlation between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) scores. Materials and Methods: The patients were divided into three groups according to their SYNTAX score. Group 1 included patients with a SYNTAX score <23, group 2 with a SYNTAX score of 23-32, and group 3 with a SYNTAX score of >33. PLR was calculated as the ratio of platelet count to lymphocyte count. Results: In multivariate logistic regression analysis, high PLR and NLR ratios and older age were independent predictors of high SYNTAX score II [odds ratio (OR): 1.052; 95% confidence interval (CI): (0.998-1.119), p=0.011; OR: 1.093; 95% CI: (1.016-1.175), p=0.016; OR:1.023; 95% CI: (1.0101.038), p=0.001, respectively. Patients with high PLR had significantly higher SYNTAX scores [121.7 (114.2-129.3) in group 1; 139.4 (125.9-153.0) in group 2, 187.0 (141.8-232.2) in group 3; p<0.001], and there was a positive correlation between PLR, NLR and SYNTAX scores (r=0.52, p<0.001; r=0.58, p<0.001, respectively). Conclusion: PLR and NLR were associated with the severity and complexity of coronary artery disease in patients with acute ST-elevation myocardial infarction.
dc.description.sponsorshipFinancial Disclosure: The authors declared that this study received no financial support.
dc.identifier.doi10.4274/nkmj.galenos.2024.97268
dc.identifier.endpage175
dc.identifier.issn2587-0262
dc.identifier.issue3
dc.identifier.startpage171
dc.identifier.trdizinid1282778
dc.identifier.urihttps://doi.org/10.4274/nkmj.galenos.2024.97268
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay1282778
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23915
dc.identifier.volume12
dc.identifier.wosWOS:001325743200004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherGalenos Publ House
dc.relation.ispartofNamik Kemal Medical Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectLymphocytes; neutrophils; coronary artery disease; inflammation
dc.titlePredictors of Severity of Coronary Artery Disease in Patients with Acute ST-elevation Myocardial Infarction
dc.typeArticle

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