The prognostic value of rapid risk scores among patients with community-acquired pneumonia: A retrospective cohort study

dc.contributor.authorİlhan, Buğra
dc.contributor.authorBozdereli Berikol, Göksu
dc.contributor.authorDoğan, Halil
dc.date.accessioned2025-01-21T16:28:57Z
dc.date.available2025-01-21T16:28:57Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: Community-acquired pneumonia (CAP) is a frequent reason for emergency department (ED) presentations. Various risk scores have been validated in the management of CAP and are recommended for daily practice. Objective: The aim of the study was to evaluate the performance of the rapid risk scores (the rapid acute physiology score (RAPS), the rapid emergency medicine score (REMS), the Worthing physiological scoring system (WPS), CURB-65 and CRB-65) among patients with CAP. Methods: This retrospective cohort study was conducted in the ED of a tertiary hospital between 1 January 2019 and 31 December 2019. Patients aged ??18 years and diagnosed with CAP were included. Patients who were transferred from another center or with missing records were excluded. Demographic information, vital signs, level of consciousness, laboratory results, and outcomes were recorded. Results: A total of 2057 patients were included in the final analysis. The 30-day mortality of the patients was 15.2% (n?= 312). The WPS achieved the most successful results for all three outcomes, 30-day mortality, intensive care unit (ICU) admission and mechanical ventilation (MV) needs (area under the curve, AUC 0.810, 0.918, and 0.910, respectively; p?< 0.001). In the prediction of mortality, RAPS, REMS, CURB-65, and CRB-65 had a moderate overall performance (AUC 0.648, 0.752, 0.778, and 0.739, respectively). In the prediction of ICU admission and MV needs, RAPS, REMS, CURB-65, and CRB-65 had moderate to good overall performance (AUC at ICU admission 0.793, 0.873, 0.829, and 0.810; AUC for MV needs 0.759, 0.892, 0.754, and 0.738, respectively). Advanced age, lower levels of mean arterial pressure and peripheral oxygen saturation, presence of active malignancy and cerebrovascular disease, and ICU admission were associated with mortality (p?< 0.05). Conclusion: The WPS outperformed other risk scores in patients with CAP and can be used safely. The CRB-65 can be used to discriminate critically ill patients with CAP due to its high specificity. The overall performances of the scores were satisfactory for all three outcomes. © 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.
dc.identifier.doi10.1007/s00508-023-02238-9
dc.identifier.endpage516
dc.identifier.issn0043-5325
dc.identifier.issue19-20
dc.identifier.pmid37405488
dc.identifier.scopus2-s2.0-85163963517
dc.identifier.scopusqualityQ1
dc.identifier.startpage507
dc.identifier.urihttps://doi.org/10.1007/s00508-023-02238-9
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23655
dc.identifier.volume135
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSpringer
dc.relation.ispartofWiener Klinische Wochenschrift
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectCommunity-acquired pneumonia; CRB-65; CURB-65; Rapid acute physiology score; Rapid emergency medicine score; Worthing physiological scoring system
dc.titleThe prognostic value of rapid risk scores among patients with community-acquired pneumonia: A retrospective cohort study
dc.typeArticle

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