The Association Between Atherogenic Index of Plasma and No-Reflow Phenomenon in Acute Coronary Syndrome

Basit Öğe Kaydı
dc.contributor.authorCelik, Ibrahim Etem
dc.contributor.authorOzturk, Selcuk
dc.contributor.authorYarlioglu, Mikail
dc.contributor.authorBarutcu, Ozan
dc.contributor.authorAkgun, Onur
dc.contributor.authorDuran, Mustafa
dc.contributor.authorYorulmaz, Sukru
dc.date.accessioned2025-01-21T16:44:53Z
dc.date.available2025-01-21T16:44:53Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: The atherogenic index of plasma (AIP) is a biomarker of plasma atherogenicity. Elevated AIP is linked with adverse cardiac events. We sought to examine the association of admission AIP and no-reflow phenomenon (NRP) in acute coronary syndrome (ACS) patient population treated with percutaneous coronary intervention (PCI).Methods: Eight hundred eight-four ACS patients were included to statistical tests retrospectively and classified according to the occurrence of NRP: NRP (-) (n = 662) and NRP (+) (n = 186). AIP levels were calculated through the formula log10 (trig lycer ide-t o-hig h-den sity lipoprotein cholesterol ratio).Results: AIP levels were higher in NRP (+) patients compared to NRP (-) group patients. The receiver operating characteristic (ROC) curve analysis for AIP to predict NRP yielded an area under the ROC curve value 0.643 [95% confidence interval (CI): 0.596-0.690, P < .001]. AIP was associated with NRP in univariate logistic regression analysis [Odds Ratio (OR): 2.46; P = .001; CI: 1.44 (lower limit)-4.21 (upper limit)]. However, AIP did not emerge as a significant prognostic factor of NRP in multiple logistic regression analysis [OR: 2.11; P = .422; CI: 0.34 (lower limit)-13.11 (upper limit)]. On the other hand, peak troponin T (log10) was an independent prognostic factor for NRP [OR: 0.13; P < .001; CI: 0.10 (lower limit)-0.37 (upper limit)] occurrence.Conclusion: The AIP level on admission is not a statistically significant prognostic factor of NRP. However, peak troponin T (log10) is an independent prognostic parameter of NRP.
dc.identifier.doi10.14744/AnatolJCardiol.2023.3381
dc.identifier.endpage719
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue12
dc.identifier.pmid37807878
dc.identifier.startpage712
dc.identifier.urihttps://doi.org/10.14744/AnatolJCardiol.2023.3381
dc.identifier.urihttps://hdl.handle.net/20.500.12587/25542
dc.identifier.volume27
dc.identifier.wosWOS:001119292200004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherKare Publ
dc.relation.ispartofAnatolian Journal of Cardiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectAcute coronary syndrome; atherogenic index of plasma; atherosclerosis; no-reflow phenomenon; troponin
dc.titleThe Association Between Atherogenic Index of Plasma and No-Reflow Phenomenon in Acute Coronary Syndrome
dc.typeArticle

Dosyalar

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu