Plasma Leptin, Nesfatin 1, NPY, and Zinc Levels in Obese and Metabolic Syndrome Children

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dc.authoridBaltacı, Saltuk Buğra/0000-0002-9752-7508
dc.authoridBüyükinan, Muammer/0000-0002-2937-823X
dc.authoridMenevşe, Esma/0000-0002-5477-5667
dc.contributor.authorAydoğdu, Adnan
dc.contributor.authorÜnal, Ömer
dc.contributor.authorBaltacı, Saltuk Buğra
dc.contributor.authorMenevşe, Esma
dc.contributor.authorMoğulkoç, Rasim
dc.contributor.authorErdem, Said Sami
dc.contributor.authorBüyükinan, Muammer
dc.date.accessioned2025-01-21T16:33:46Z
dc.date.available2025-01-21T16:33:46Z
dc.date.issued2023
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: The aim of this study is to investigate the relationship between leptin, nesfatin 1 and NPY hormones and zinc in boys and girls diagnosed with metabolic syndrome and obesity. Methods: This study included a total of 6 groups. Group 1 Boy Control, Group 2 Girl Control, Group 3 Obese Boys, Group 4 Obese Girls, Group 5 Boys with Metabolic Syndrome, Group 2 with Girls with Metabolic Syndrome. Plasma leptin, nesfatin-1, NPY (by ELISA method) and serum zinc (by AA method) levels were determined in blood samples obtained from the subjects. Results: Leptin and zinc levels were significantly higher both in boy and girl patients with metabolic syndrome than in obese and control children. Nesfatin-1 and NPY levels were significantly lower both in girl and boy obese and metabolic syndrome children compared to their control groups. Conclusion: In the current study a significant increase in plasma leptin and serum zinc levels and a significant decrease of plasma nesfatin-1 and NPY levels were observed in boys and girls with metabolic syndrome. The findings of our study show that leptin, nesfatin-1 and NPY levels may be important biomarkers in the assessment of metabolic syndrome risk in both girls and boys.
dc.description.sponsorshipScientific Research Projects Coordinatorship of Selcuk University [15202008]
dc.description.sponsorshipThis study was supported by the Scientific Research Projects Coordinatorship of Selcuk University (SUBAPK; project no. 15202008).
dc.identifier.doi10.58600/eurjther1760
dc.identifier.endpage865
dc.identifier.issn2564-7784
dc.identifier.issn2564-7040
dc.identifier.issue4
dc.identifier.startpage856
dc.identifier.trdizinid1221458
dc.identifier.urihttps://doi.org/10.58600/eurjther1760
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay1221458
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23853
dc.identifier.volume29
dc.identifier.wosWOS:001162350300020
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherPera Yayincilik Hizmetleri
dc.relation.ispartofEuropean Journal of Therapeutics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectChildren; metabolic syndrome; obesity; leptin; nesfatin 1; NPY; zinc
dc.titlePlasma Leptin, Nesfatin 1, NPY, and Zinc Levels in Obese and Metabolic Syndrome Children
dc.typeArticle

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