The comparison of the analgesic effect of dexketoprofen trometamol with lornoxicam and placebo on post-cesarean delivery pain

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dc.contributor.authorAykaç E.
dc.contributor.authorBüyükkoçak Ü.
dc.contributor.authorKöse E.A.
dc.contributor.authorSağsöz N.
dc.date.accessioned2020-06-25T15:17:15Z
dc.date.available2020-06-25T15:17:15Z
dc.date.issued2012
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: The aim was to compare the effect of dexketoprofen trometamol with lornoxicam and placebo on post-cesarean delivery pain. Method: Ninety patients scheduled for cesarean-section under spinal anesthesia were randomized equally into three groups. Before the surgical incision closure, 50 mg dexketoprofen trometamol (Group D), 8 mg lornoxicam (Group L) or 0.9% NaCl (Group P) was given intravenously. After the surgery all patients received intravenous tramadol via patient controlled analgesia device (bolus dose: 20 mg, lock out: 10 min.). Postoperative pain was assessed by visual analog scale (VAS). Additional analgesic doses of tramadol (20 mg, i.v) were given when the VAS value was ? 3. The time of the first analgesic requirement, VAS values at the 1, 3, 6, 12, 24 hours of the postoperative period, additional analgesic doses of tramadol, cumulative tramadol consumption, patient satisfaction, adverse effects of drugs were recorded. Results: The time of the first analgesic requirement was significantly longer and the VAS values at the postoperative first hour was significantly lower in the Group D than the Group L (p=0.01, p=0.007; respectively). The cumulative tramadol consumption and patient satisfaction was similar between the Group D and Group L. The additional analgesic consumption at postoperative first hour was significantly lower in the Group D when compared to Group L and Group P (p=0.01, p<0.001; respectively). The total additional analgesic consumption at the end of the postoperative 24 hours was lower in the Group D when compared to Group P and Group L (p=0.01, p<0.001; respectively). Conclusion: Dexketoprofen trometamol had more analgesic efficacy for postoperative pain at early postoperative period with prolonged first analgesic requirement time, decreased additional analgesic requirement, decreased VAS values in the first postoperative hour, when compared with lornoxicam.en_US
dc.identifier.endpage85en_US
dc.identifier.issn13000578
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84862988437
dc.identifier.scopusqualityQ4
dc.identifier.startpage80en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2234
dc.identifier.volume20en_US
dc.indekslendigikaynakScopus
dc.language.isotr
dc.relation.ispartofAnestezi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnalgesia, patient controlleden_US
dc.subjectCesarean-Sectionen_US
dc.subjectDexketoprofen trometamolen_US
dc.subjectLornoxicamen_US
dc.subjectTramadolen_US
dc.titleThe comparison of the analgesic effect of dexketoprofen trometamol with lornoxicam and placebo on post-cesarean delivery painen_US
dc.title.alternativeSezaryen i?le doğum sonrasi ağrida deksketoprofen trometamolün analjezi?k etki?si?ni?n lornoksi?kam ve plasebo i?le karşilaştirilmasien_US
dc.typeArticle

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