The comparison of the analgesic effect of dexketoprofen trometamol with lornoxicam and placebo on post-cesarean delivery pain
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Tarih
2012
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: The aim was to compare the effect of dexketoprofen trometamol with lornoxicam and placebo on post-cesarean delivery pain. Method: Ninety patients scheduled for cesarean-section under spinal anesthesia were randomized equally into three groups. Before the surgical incision closure, 50 mg dexketoprofen trometamol (Group D), 8 mg lornoxicam (Group L) or 0.9% NaCl (Group P) was given intravenously. After the surgery all patients received intravenous tramadol via patient controlled analgesia device (bolus dose: 20 mg, lock out: 10 min.). Postoperative pain was assessed by visual analog scale (VAS). Additional analgesic doses of tramadol (20 mg, i.v) were given when the VAS value was ? 3. The time of the first analgesic requirement, VAS values at the 1, 3, 6, 12, 24 hours of the postoperative period, additional analgesic doses of tramadol, cumulative tramadol consumption, patient satisfaction, adverse effects of drugs were recorded. Results: The time of the first analgesic requirement was significantly longer and the VAS values at the postoperative first hour was significantly lower in the Group D than the Group L (p=0.01, p=0.007; respectively). The cumulative tramadol consumption and patient satisfaction was similar between the Group D and Group L. The additional analgesic consumption at postoperative first hour was significantly lower in the Group D when compared to Group L and Group P (p=0.01, p<0.001; respectively). The total additional analgesic consumption at the end of the postoperative 24 hours was lower in the Group D when compared to Group P and Group L (p=0.01, p<0.001; respectively). Conclusion: Dexketoprofen trometamol had more analgesic efficacy for postoperative pain at early postoperative period with prolonged first analgesic requirement time, decreased additional analgesic requirement, decreased VAS values in the first postoperative hour, when compared with lornoxicam.
Açıklama
Anahtar Kelimeler
Analgesia, patient controlled, Cesarean-Section, Dexketoprofen trometamol, Lornoxicam, Tramadol
Kaynak
Anestezi Dergisi
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
20
Sayı
2
