Advanced oxidation protein products and monocyte chemoattractant protein-1 in periodontal disease
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Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aim: The aim of the study was to determine gingival crevicular fluid (GCF) levels of advanced oxidation protein product(AOPP) and monocyte chemoattractant protein (MCP)-1 in subjects with periodontal disease and health.Materials and Methods: A total of 75 non-smokers, including 25 participants with chronic periodontitis (CP), 25participants with gingivitis (G) and 25 participants with periodontally healthy (H) were included into the present study.The probing depth (PD), clinical attachment level (CAL), plaque index (PI) and gingival index (GI) were recorded. The GCFsamples from 4 sites in each individual were collected and GCF AOPP and MCP-1 levels were determined by enzymelinked immunosorbent assay method.Results: GCF AOPP and MCP-1 levels were the lowest in the H group; followed by the G group and the highest in the CPgroup. These differences were statistically significant between G and H groups and between the CP and the other groups(p <.05). A statistically positive correlation was detected between GCF AOPP and MCP-1 levels.Conclusion: GCF AOPP and MCP-1 levels might play a considerable role during periodontal inflammation and an elevatedGCF AOPP and MCP-1 levels are suggested as a potential biomarker for periodontal diseases.
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp, Tıbbi Laboratuar Teknolojisi
Kaynak
Turkish Journal of Clinics and Laboratory
WoS Q Değeri
Scopus Q Değeri
Cilt
9
Sayı
1
