Advanced oxidation protein products and monocyte chemoattractant protein-1 in periodontal disease

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dc.contributor.authorHendek, Meltem Karşıyaka
dc.contributor.authorErdemir, Ebru Olgun
dc.contributor.authorKısa, Üçler
dc.date.accessioned2025-01-21T16:17:23Z
dc.date.available2025-01-21T16:17:23Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.description.abstractAim: The aim of the study was to determine gingival crevicular fluid (GCF) levels of advanced oxidation protein product(AOPP) and monocyte chemoattractant protein (MCP)-1 in subjects with periodontal disease and health.Materials and Methods: A total of 75 non-smokers, including 25 participants with chronic periodontitis (CP), 25participants with gingivitis (G) and 25 participants with periodontally healthy (H) were included into the present study.The probing depth (PD), clinical attachment level (CAL), plaque index (PI) and gingival index (GI) were recorded. The GCFsamples from 4 sites in each individual were collected and GCF AOPP and MCP-1 levels were determined by enzymelinked immunosorbent assay method.Results: GCF AOPP and MCP-1 levels were the lowest in the H group; followed by the G group and the highest in the CPgroup. These differences were statistically significant between G and H groups and between the CP and the other groups(p <.05). A statistically positive correlation was detected between GCF AOPP and MCP-1 levels.Conclusion: GCF AOPP and MCP-1 levels might play a considerable role during periodontal inflammation and an elevatedGCF AOPP and MCP-1 levels are suggested as a potential biomarker for periodontal diseases.
dc.identifier.doi10.18663/tjcl.328204
dc.identifier.endpage6
dc.identifier.issn2149-8296
dc.identifier.issue1
dc.identifier.startpage1
dc.identifier.trdizinid413638
dc.identifier.urihttps://doi.org/10.18663/tjcl.328204
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/413638
dc.identifier.urihttps://hdl.handle.net/20.500.12587/22626
dc.identifier.volume9
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.relation.ispartofTurkish Journal of Clinics and Laboratory
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectGenel ve Dahili Tıp
dc.subjectTıbbi Laboratuar Teknolojisi
dc.titleAdvanced oxidation protein products and monocyte chemoattractant protein-1 in periodontal disease
dc.typeArticle

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