Effects of Gold Nanoparticles on Angiogenesis in A Chick Chorioallantoic Membrane Model

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dc.contributor.authorCirik, Samet
dc.contributor.authorElesad, Musa
dc.contributor.authorBasar, Ebrar
dc.contributor.authorAksu, Elif
dc.contributor.authorErdem, Muaz
dc.contributor.authorYildiztekin, Faruk
dc.contributor.authorMenekse, Sinan
dc.date.accessioned2021-01-14T18:10:22Z
dc.date.available2021-01-14T18:10:22Z
dc.date.issued2020
dc.departmentKKÜ
dc.description.abstractObjective: Today, nanotechnology is widely used in many fields because of its ability to alter the structure of molecules at the atomic level. Metallic nanoparticles attracted great attention from researchers because of their unique properties. Based on the notable features of gold nanoparticles (AuNPs), they have long been evaluated as a potential diagnostic tool for several cancers and for drug delivery applications. Angiogenesis is the development of new vessels that support embryonic up growth and critically modulate many biological processes through adulthood. The inhibition of angiogenesis causes regression of development and metastasis of malign tumours. In this study we aim to examine the effects of AuNPs on angiogenesis in an in vivo chick chorioallantoic membrane (CAM) model. Methods: We applied 20 mL concentrations of AuNPs solution to 24 eggs of the CAM on the fifth day. After then, we evaluated results macroscopically on the 6th and 7th days. Results: In our study, we observed that AuNPs induced angiogenesis. Conclusion: We suggest that AuNPs may not be ideal nanoparticles to make biosensors due to increasing angiogenesis during the course of cancers.en_US
dc.identifier.citationCırık S, Elesad M, Başar E, Aksu E, Erdem M, Yıldıztekin F, Menekşe S, Çelikel R, İpek M, Fermanlı O, Eşrefoğlu M (2020). Effects of Gold Nanoparticles on Angiogenesis in A Chick Chorioallantoic Membrane Model. Bezmiâlem Science, 8(4), 398 - 402. 10.en_US
dc.identifier.doi10.14235/bas.galenos.2020.3668
dc.identifier.endpage402en_US
dc.identifier.issn2148-2373
dc.identifier.issue4en_US
dc.identifier.startpage398en_US
dc.identifier.trdizinid459045
dc.identifier.urihttps://doi.org/10.14235/bas.galenos.2020.3668
dc.identifier.urihttps://hdl.handle.net/20.500.12587/12553
dc.identifier.volume8en_US
dc.identifier.wosWOS:000600293100012
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherBEZMIALEM VAKIF UNIVen_US
dc.relation.ispartofBEZMIALEM SCIENCE
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAngiogenesisen_US
dc.subjectchorioallantoic membraneen_US
dc.subjectgold nanoparticlesen_US
dc.subjectcanceren_US
dc.titleEffects of Gold Nanoparticles on Angiogenesis in A Chick Chorioallantoic Membrane Modelen_US
dc.typeArticle

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