Crevicular fluid levels of interleukin-8, interleukin-17 and soluble intercellular adhesion molecule-1 after regenerative periodontal therapy

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dc.contributor.authorErdemir E.O.
dc.contributor.authorHendek M.K.
dc.contributor.authorKeceli H.G.
dc.contributor.authorApan T.Z.
dc.date.accessioned2020-06-25T15:17:34Z
dc.date.available2020-06-25T15:17:34Z
dc.date.issued2015
dc.departmentKırıkkale Üniversitesi
dc.description.abstractObjective: The aim of this study is to evaluate the influence of regenerative periodontal therapy on clinical parameters and interleukin-8 (IL-8), IL-17 and soluble intercellular adhesion molecule-1 (sICAM-1) levels in gingival crevicular fluid (GCF) of subjects with chronic periodontitis (CP). Materials and Methods: Fifteen patients received demineralized freeze-dried bone allograft (DFDBA) surgically to the site of infrabony defect. Clinical periodontal indices were recorded, and GCF samples were collected at baseline and at the 6th and the 9th month after the surgery. Results: Except plaque index, all clinical parameters improved following surgery (P < 0.05). The volume of GCF diminished from baseline to follow-up periods (P < 0.05). However, no effect was observed on the total amount of IL-8, IL-17 and sICAM-1 in GCF. Conclusion: DFDBA improved clinical outcome in CP subjects and was effective on decreasing the volume of GCF, but no effect was determined on IL-8, IL-17 and sICAM-1. Findings did not indicate a direct relationship between biochemical parameters and periodontal healing after demineralized freeze-dried bone grafting. © 2015 Dental Investigations Society.en_US
dc.identifier.doi10.4103/1305-7456.149644
dc.identifier.endpage65en_US
dc.identifier.issn13057456
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-84921732368
dc.identifier.scopusqualityQ1
dc.identifier.startpage60en_US
dc.identifier.urihttps://doi.org/10.4103/1305-7456.149644
dc.identifier.urihttps://hdl.handle.net/20.500.12587/2434
dc.identifier.volume9en_US
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherDental Investigations Societyen_US
dc.relation.ispartofEuropean Journal of Dentistry
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDemineralized freeze-dried bone allograften_US
dc.subjectGingival crevicular fluiden_US
dc.subjectInterleukin-17en_US
dc.subjectInterleukin-8en_US
dc.subjectSoluble intercellular adhesion molecule-1en_US
dc.titleCrevicular fluid levels of interleukin-8, interleukin-17 and soluble intercellular adhesion molecule-1 after regenerative periodontal therapyen_US
dc.typeArticle

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