Thermoresponsive and biocompatible poly(vinyl alcohol)-graft-poly(N,N-diethylacrylamide) copolymer: Microwave-assisted synthesis, characterization, and swelling behavior

Basit Öğe Kaydı
dc.contributor.authorIsiklan, Nuran
dc.contributor.authorKazan, Hacer
dc.date.accessioned2020-06-25T18:29:41Z
dc.date.available2020-06-25T18:29:41Z
dc.date.issued2018
dc.departmentKırıkkale Üniversitesi
dc.description.abstractNovel thermoresponsive poly(vinyl alcohol)-graft-poly(N,N-diethylacrylamide) (PVA-g-PDEAAm) copolymers were prepared by microwave-assisted graft copolymerization using a potassium persulfate/N,N,N,N-tetramethylethylenediamine (KPS/TEMED) initiator system. The structures of PVA-g-PDEAAm copolymers were characterized by H-1-NMR, Fourier transform infrared spectroscopy, differential scanning calorimetry/thermogravimetric analysis, gel permeation chromatography, X-ray diffraction, and scanning electron microscopy. The effects of various process parameters on grafting were systematically studied: microwave power, KPS, monomer and PVA concentrations, and ultraviolet irradiation. Under optimal conditions, the maximum grafting percent and graft efficiency were 101% and 93%, respectively. Furthermore, a lower critical temperature of copolymers was measured in the range 29-31 degrees C by ultraviolet spectroscopy. The swelling behavior of graft membranes was carried out at various temperatures, and the results showed that the swelling behavior of membranes was dependent on the temperature. In vitro cell culture studies using L929 fibroblast cells confirmed cell compatibility with the PVA-g-PDEAAm copolymer and its membrane, making them an attractive candidate for drug delivery systems. (c) 2017 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 45969.en_US
dc.description.sponsorshipTUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [113Z271]en_US
dc.description.sponsorshipThis study is financially supported by the TUBITAK with the grant number 113Z271.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1002/app.45969
dc.identifier.issn0021-8995
dc.identifier.issn1097-4628
dc.identifier.issue12en_US
dc.identifier.scopus2-s2.0-85035210568
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1002/app.45969
dc.identifier.urihttps://hdl.handle.net/20.500.12587/7422
dc.identifier.volume135en_US
dc.identifier.wosWOS:000417917200009
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Applied Polymer Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcopolymersen_US
dc.subjectgraftingen_US
dc.subjectradical polymerizationen_US
dc.subjectstimuli-sensitive polymersen_US
dc.titleThermoresponsive and biocompatible poly(vinyl alcohol)-graft-poly(N,N-diethylacrylamide) copolymer: Microwave-assisted synthesis, characterization, and swelling behavioren_US
dc.typeArticle

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
The Effects of Periostin in a Rat Model of Isoproterenol Mediated Cardiotoxicity.pdf
Boyut:
3.77 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin/Full Text
İndir

Koleksiyon

WOS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu