Çocuklarda Helicobacter pylori seroprevalansı ve etki eden faktörler
[ X ]
Tarih
2006
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Helicobacter pylori ve cagA prevalansını belirlemek ve buna etki eden faktörleri saptamak amacıyla toplam 235 çocukta yapılan bu çalışmada özgül IgG'ler ve cagA seroprevalansının saptanmasında ELISA kullanılmıştır. Çocuklarda H. pylori seropozitifliği %34.9 (82/235) ve H. pylori IgG'si pozitif olanlarda saptanan cagA seropozitifliği %20.7 (17/82)'dir. Helicobacter pylori ve cagA seroprevalansının yaş grupları ve cinsiyete göre istatistiksel olarak farklılık göstermediği görülmüştür. Kabakulak ve solunum sinsityal virus seropozitiflik oranları %43.4 ve %86'dır. Solunum sinsityal virus ve H. pylori serolojisi arasında anlamlı derecede farklılık (p0.001) olmasına rağmen kabakulakla H. pylori serolojisi arasında fark görülmemiştir (p0.059). Solunum yoluyla bulaşmasına rağmen daha yakın temas gerektiren kabakulak virusunda olduğu gibi H. pyloriY\in de bulaşabilmesi için yakın temasın gerekli olduğu düşünülebilir. Sonuç olarak, çocuklarda H. pylori infeksiyonu prevalansı yüksek olmasına rağmen cagA fenotipine sahip olan suşların oranının düşük olması bir avantaj olarak görülebilir.
This study was performed to investigate the prevalence of Helicobacter pylori infection and cagA as well as factors affecting this prevalence in 235 children. ELISA was used for determining the seroprevalence of special IgG and cagA. Seropositiveness of H. pylori infection was 34.9% in children. Seropositiveness of cagA was 20.7% in children in whom H. pylori IgG was positive. It was found that there was no statistical difference in the seroprevalence of H. pylori and cagA when gender and age groups were compared. The ratios of seropositivity of mumps and respiratory syncytial virus infection were 43.4% and 86%, respectively. Although there was a significant difference between the serology of the respiratory sinsitial virus and H. pylori (p<0,001), no difference was detected between the serology of the mumps and H. pylori (p0.059). Like mumps which spreads via the respiratory tract with close contact, the spread of H. pylori infection could be also reqire close contact. As a result although seroprevalence of H. pylori in children was high, the low rate of H. pylori strains which had fenotype of cagA might be considered as an advantage.
This study was performed to investigate the prevalence of Helicobacter pylori infection and cagA as well as factors affecting this prevalence in 235 children. ELISA was used for determining the seroprevalence of special IgG and cagA. Seropositiveness of H. pylori infection was 34.9% in children. Seropositiveness of cagA was 20.7% in children in whom H. pylori IgG was positive. It was found that there was no statistical difference in the seroprevalence of H. pylori and cagA when gender and age groups were compared. The ratios of seropositivity of mumps and respiratory syncytial virus infection were 43.4% and 86%, respectively. Although there was a significant difference between the serology of the respiratory sinsitial virus and H. pylori (p<0,001), no difference was detected between the serology of the mumps and H. pylori (p0.059). Like mumps which spreads via the respiratory tract with close contact, the spread of H. pylori infection could be also reqire close contact. As a result although seroprevalence of H. pylori in children was high, the low rate of H. pylori strains which had fenotype of cagA might be considered as an advantage.
Açıklama
Anahtar Kelimeler
Enfeksiyon Hastalıkları
Kaynak
İnfeksiyon Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
20
Sayı
4
Künye
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