Dietary Acid Load Associated with Hypertension and Diabetes in the Elderly

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dc.contributor.authorOmma, Tulay
dc.contributor.authorGulcelik, Nese Ersoz
dc.contributor.authorZengin, Fatmanur Humeyra
dc.contributor.authorKarahan, Irfan
dc.contributor.authorCulha, Cavit
dc.date.accessioned2025-01-21T16:27:16Z
dc.date.available2025-01-21T16:27:16Z
dc.date.issued2022
dc.departmentKırıkkale Üniversitesi
dc.description.abstractBackground: Diet can affect the body's acid-base balance due to its content of acid or base precursors. There is conflicting evidence for the role of metabolic acidosis in the development of cardiometabolic disorders, hypertension (HT), and insulin resistance (IR). Objective: We hypothesized that dietary acid load (DAL) is associated with adverse metabolic risk factors and aimed to investigate this in the elderly. Methods: A total of 114 elderly participants were included in the study. The participants were di-vided into four groups, such as HT, diabetes (DM), both HT and DM, and healthy controls. An-thropometric, biochemical, and clinical findings were recorded. Potential renal acid load (PRAL) and net endogenous acid production (NEAP) results were obtained for three days, 24-hour dietary records via a nutrient database program (BeBiS software program). Results: The groups were matched for age, gender, and BMI. There was a statistically significant difference between the groups regarding NEAP (p =0.01) and no significant difference for PRAL (p = 0.086). The lowest NEAP and PRAL levels were seen in the control group while the highest in the HT group. Both NEAP and PRAL were correlated with waist circumference (r = 0,325, p = 0.001; r=0,231, p =0,016, respectively). Conclusion: Our data confirmed that subjects with HT and DM had diets with greater acid-forming potential. High NEAP may be a risk factor for chronic metabolic diseases, particularly HT. PRAL could not be shown as a significantly different marker in all participants. Dietary content has a significant contribution to the reduction of cardiovascular risk factors, such as HT, DM, and obesity. © 2022 Bentham Science Publishers.
dc.identifier.doi10.2174/1874609815666220328123744
dc.identifier.endpage251
dc.identifier.issn1874-6098
dc.identifier.issue3
dc.identifier.pmid35346013
dc.identifier.scopus2-s2.0-85134631459
dc.identifier.scopusqualityQ3
dc.identifier.startpage242
dc.identifier.urihttps://doi.org/10.2174/1874609815666220328123744
dc.identifier.urihttps://hdl.handle.net/20.500.12587/23310
dc.identifier.volume15
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherBentham Science Publishers
dc.relation.ispartofCurrent Aging Science
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.snmzKA_20241229
dc.subjectdiabetes; Dietary acid load; hypertension; insulin resistance; net endogenous acid production; potential renal acid load
dc.titleDietary Acid Load Associated with Hypertension and Diabetes in the Elderly
dc.typeArticle

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