A versatile plug microvalve for microfluidic applications

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dc.contributor.authorGuler, M. Tahsin
dc.contributor.authorBeyazkilic, Pinar
dc.contributor.authorElbuken, Caglar
dc.date.accessioned2020-06-25T18:22:40Z
dc.date.available2020-06-25T18:22:40Z
dc.date.issued2017
dc.departmentKırıkkale Üniversitesi
dc.descriptionGULER, MUSTAFA TAHSIN/0000-0002-0478-3183; Elbuken, Caglar/0000-0001-8359-6871
dc.description.abstractMost of the available microvalves include complicated fabrication steps and multiple materials. We present a microvalve which is inspired from macroplug valves. The plug microvalve is fabricated by boring a hole through a rigid cylindrical rod and inserting it through a microfluidic chip. It simply functions by rotating the rod which aligns or misaligns the valve port with the microchannel. The rod is made up of a rigid material for applying the valve to an elastic polydimethylsiloxane (PDMS) microchannel. The valve can also be used for a rigid channel by inserting the rod into an elastic tubing. Therefore, the presented microvalve can be used for both elastomeric and thermoplastic channels. The plug microvalve can be applied to a prefabricated microchannel and does not require modification of the mold design. We have verified the repeatability and robustness of the valve by repetitive operation cycles using a servo motor. The plug microvalve is adaptable to numerous microfluidic applications. We have shown three modes of operation for the microvalve including fluid flow control across multiple intersecting channels. Integrating the microvalve to some commonly used microfluidic designs, we demonstrated the versatility and the practicality of the microvalve for controlling flow focusing, microdroplet sorting and rapid chemical agent detection. This low-cost microvalve significantly minimizes the prototyping time for microfluidic systems. (C) 2017 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipEuropean Union FP7 Marie Curie Career Integration Grant [322019]; TUBITAK-BIDEB graduate fellowshipen_US
dc.description.sponsorshipThis project was partially supported by European Union FP7 Marie Curie Career Integration Grant (no. 322019). P. B. is supported by TUBITAK-BIDEB graduate fellowship. The authors also thank Murat Serhatlioglu for his help on the figures, Ziya Isiksacan and Resul Saritas for critical reading of the manuscript.en_US
dc.identifier.citationclosedAccessen_US
dc.identifier.doi10.1016/j.sna.2017.09.001
dc.identifier.endpage230en_US
dc.identifier.issn0924-4247
dc.identifier.scopus2-s2.0-85029074798
dc.identifier.scopusqualityQ1
dc.identifier.startpage224en_US
dc.identifier.urihttps://doi.org/10.1016/j.sna.2017.09.001
dc.identifier.urihttps://hdl.handle.net/20.500.12587/6856
dc.identifier.volume265en_US
dc.identifier.wosWOS:000413381400027
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherElsevier Science Saen_US
dc.relation.ispartofSensors And Actuators A-Physical
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectValveen_US
dc.subjectMicrovalveen_US
dc.subjectPortable microfluidicsen_US
dc.subjectColorimetric TNT assayen_US
dc.titleA versatile plug microvalve for microfluidic applicationsen_US
dc.typeArticle

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