Investigation of Pneumocystis Jiroveci Carriage in Patients with Various Lung Diseases

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dc.contributor.authorKaygusuz, Sedat
dc.contributor.authorErtürk, Arzu
dc.contributor.authorKılıç, Dilek
dc.contributor.authorKonur, Özcan
dc.contributor.authorKubar, Ayhan
dc.date.accessioned2025-01-21T14:27:33Z
dc.date.available2025-01-21T14:27:33Z
dc.date.issued2008
dc.description.abstractPneumocyctis jiroveci is one of the major reasons of morbidity especially in immunosuppressive individuals. Recently, a large number of asymptomatic colonization has been noted. The aim is to investigate the frequency of P. jiroveci colonization in patients (Group I) with lung cancer who do not take oral corticosteroid and the patients (Group II) with other lung problems by using immunofluorescence (IF) method and polymerase chain reaction.Incidence of P. jiroveci has been investigated in the bronchoalveolar lavage samples taken by bronchoscopy for diagnose and treatment by using IF method and P. jiroveci DNA has been defined with PCR method.In Group I, 1 (1.8%) IF and 3 (5.5%) PCR positivism (one of them is the case which is found positive by using IF method) have been acquired. In Group II, both of the methods have produced no positivism.Colonization of P. jiroveci is noted in patients with HIV negative. The fact that the cases only with lung cancer have positivity supports the idea that lung cancer is important risk factor. The patients with lung cancer should be monitored closely for prophylaxis and treatment and the treatment should not be applied to each PCR positive case.
dc.identifier.dergipark124772
dc.identifier.issn2148-9645
dc.identifier.issue1-42
dc.identifier.startpage47
dc.identifier.urihttps://dergipark.org.tr/tr/download/article-file/106541
dc.identifier.urihttps://dergipark.org.tr/tr/pub/kutfd/issue/10147/124772
dc.identifier.urihttps://hdl.handle.net/20.500.12587/20124
dc.identifier.volume1
dc.language.isotr
dc.publisherKırıkkale Üniversitesi
dc.relation.ispartofKırıkkale Üniversitesi Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_20241229
dc.subjectPneumocyctis jiroveci
dc.subjectPCR
dc.subjectimmunofluorescence
dc.subjectlung carcinoma
dc.subjectHealth Care Administration
dc.subjectSağlık Kurumları Yönetimi
dc.titleInvestigation of Pneumocystis Jiroveci Carriage in Patients with Various Lung Diseases
dc.typeArticle

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